Evidence map›Paper›PMID 36033828›Full record

ArticleDisease markers2022

Clinical and Basic Evaluation of the Effects of Upregulated TNFAIP3 Expression on Colorectal Cancer.

Jinhe Li, Shuang Ren, Yuhua Zhang, Bingbing Wu, Meng He, Zhen Shan, Yang Liu, Yuejing Wang

Abstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinhe Li *Department of General Surgery, Qiqihar First Hospital, Qiqihar 161006, China.
Shuang Ren *Department of Pathology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210000, China.
Yuhua Zhang *Department of General Surgery, Qiqihar First Hospital, Qiqihar 161006, China.
Bingbing WuDepartment of General Surgery, Qiqihar First Hospital, Qiqihar 161006, China.
Meng HeDepartment of General Surgery, Qiqihar First Hospital, Qiqihar 161006, China.
Zhen ShanDepartment of General Surgery, Qiqihar First Hospital, Qiqihar 161006, China.
Yang LiuDepartment of General Surgery, Qiqihar First Hospital, Qiqihar 161006, China.ORCID https://orcid.org/0000-0002-8506-9722
Yuejing WangDepartment of Embryology, Qiqihar Medical College, Qiqihar 161006, China.ORCID https://orcid.org/0000-0003-0398-4079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the TNFAIP3 and nuclear factor Methods: The following methods should be used in clinical trials: information collection and immunohistochemical methods. The following methods are used for cell experiment: cell transfection, CCK8 detection method, transwell experiment, and western blot experiment. Explore the TNFAIP3 expression in CRC cells, and assess the effect of upregulated TNFAIP3 expression on CRC cell proliferation, invasion, and migration. In clinical experiment, we selected the tumor tissues of 39 CRC patients as our experimental samples. We also collected corresponding patient demographics, such as sex, age, cell differentiation, tumor type, and lymph node metastasis. We also analyzed the TNFAIP3 and NF Results: NF Conclusion: TNFAIP3 overexpression strongly inhibited CRC proliferation, invasion, and migration. Enhanced NF

Indexed as

Colorectal NeoplasmsCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansLymphatic MetastasisNF-kappa BPrognosisTumor Necrosis Factor alpha-Induced Protein 3NF-kappa BTNFAIP3 protein, humanTumor Necrosis Factor alpha-Induced Protein 3

Identifiers

PMID36033828
PMCPMC9410822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.