ArticleFrontiers in public health2022
The Chronic Kidney Disease Epidemiology Collaboration equations perform less well in an older population with type 2 diabetes than their non-diabetic counterparts.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 8 citations in OpenAlex.
- Plasma Erythropoietin Levels and Anemia in Vietnamese Patients With Type 2 Diabetes and Chronic Kidney Disease: 2018-2019.Health science reports · 2026Article
- Short-term effect of atorvastatin on renal oxidative stress, inflammation, and fibrosis in a rat model of streptozotocin-induced diabetes.Journal of diabetes and metabolic disorders · 2025Article
- Comparison and evaluation of the 2009 and 2021 chronic kidney disease-epidemiological collaboration equations among Jordanian patients with type 2 diabetes mellitus.Acta diabetologica · 2024Article
- A back propagation neural network approach to estimate the glomerular filtration rate in an older population.BMC geriatrics · 2023Article
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Authors and funding
3 authors at 2 institutions in 1 country.
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Abstract
Objectives: The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations are based on creatinine alone (CKD-EPIcr), cystatin C alone (CKD-EPIcys) and combined creatinine and cystatin C (CKD-EPIcr-cys). It remains unclear whether these equations perform differently in older adults with type 2 diabetes than they do in non-diabetic older individuals. Methods: This single-center cross-sectional study was performed in adults aged ≥ 65 years between January 2019 and December 2021. Glomerular filtration rate (GFR) was measured by technetium-99m-diethylene triamine pentaacetic acid ( Results: Finally, 476 participants were enrolled, including 243 adults with type 2 diabetes and 233 non-diabetic adults. The mean age of the included participants was 71.69 ± 6.4 years and 262 (55%) were male. The mean measured GFR was 49.02 ± 22.45 ml/min/1.73 m Conclusions: The performance of the CKD-EPI equations was lower in a group of patients aged ≥ 65 years with type 2 diabetes than in non-diabetic counterparts. However, each equation still had limitations regarding accuracy in older adults with or without diabetes.
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