ReviewFrontiers in neuroscience2022
Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms.
Review in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
120 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review on Insomnia and Circadian Rhythms Desynchronization in Obsessive-Compulsive Disorder: From Childhood to Adulthood.Journal of sleep research · 2026Pooled it
- The Association Between Delayed Sleep-Wake Phase Disorder and Depression Among Young Individuals: A Systematic Review and Meta-Analysis: Association entre le syndrome de retard de phase et la dépression parmi les jeunes : revue systématique et méta-analyse.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2025Pooled it
- An examination of chronotype associations with symptoms of depression, PTSD, and sleep disturbances in US military veterans.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Subjective Sleep Timing and Social Jet Lag Relate to Neural Activation During Reward Feedback in Adolescence.Journal of sleep research · 2026Article
- Review
- High social jetlag in healthy youth: differences in tryptophan levels and regional gray matter volume.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Article
- Sleep quality and chronotype in primary headache disorders: a nationwide population-based study of 5,311 Polish adults.The journal of headache and pain · 2026Article
- Sleep as a moderator of adolescent brain development-evidence from a longitudinal MRI study.Sleep · 2026Article
- Beyond composite scores in chronotype assessment: item-level predictive patterns in the Morningness-Eveningness Questionnaire.Scientific reports · 2026Observational
- Population-Specific Genetic and Non-Genetic Influences on Sleep Traits and Health Outcomes.ArXiv · 2026Article
- [KLF10 overexpression alleviates neuroinflammation and anxiety-depressive disorder in rats by downregulating the NF-κB/NLRP3 pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Sleep Quality Profiles in Youth with Eating Disorders: A Latent Profile Analysis.Brain sciences · 2026Article
- Commonalities in frailty and psychopathology predict chronotype across severe mental disorders from a comorbidity perspective.Psychological medicine · 2026Article
- The association between chronotype and incident dementia: exploring age, educational-attainment and sex differences.Epidemiology and psychiatric sciences · 2026Article
- Article
- Neuroanatomical signatures of chronotype in young adults.Brain imaging and behavior · 2026Article
- Emotion regulation and depressive symptoms mediate the association between chronotype and suicidality.Acta neuropsychiatrica · 2026Article
- Independent associations and isotemporal substitution analysis of 24-hour movement behaviors and depression among Chinese older adults.BMC psychology · 2026Article
- Chronotype, Genetic Risk, Lifestyle, and Risk of Depression and Anxiety: A Prospective Cohort Study.MedComm · 2026Article
60 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The circadian rhythm is crucial for physiological and behavioral functions. Chronotype, which represents individual preferences for activity and performance, is associated with human health issues, particularly psychiatric disorders. This narrative review, which focuses on the relationship between chronotype and mental disorders, provides an insight into the potential mechanism. Recent evidence indicates that (1) the evening chronotype is a risk factor for depressive disorders and substance use disorders, whereas the morning chronotype is a protective factor. (2) Evening chronotype individuals with bipolar disorder tend to have more severe symptoms and comorbidities. (3) The evening chronotype is only related to anxiety symptoms. (4) The relationship between chronotype and schizophrenia remains unclear, despite increasing evidence on their link. (5) The evening chronotype is significantly associated with eating disorders, with the majority of studies have focused on binge eating disorders. Furthermore, the underlying mechanisms or influence factors are described in detail, including clock genes, brain characteristics, neuroendocrinology, the light/dark cycle, social factors, psychological factors, and sleep disorders. These findings provide the latest evidence on chronotypes and psychiatric disorders and serve as a valuable reference for researchers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.