Evidence map›Paper›PMID 36033571›Full record

ArticleBioMed research international2022

Effect of Dihuang Yinzi on Inflammatory Response in Cerebral Ischemia-Reperfusion Model Rats by Regulating Gut Microbiota.

Xinyu Wang, Lei Ye, Wanru Sun, Liya Li, Chaoyun Wang, Xiaoyan Xu, Zhaohai Pan, Jianwei Gong

RetractedAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Th17 Cells and IL-17A in Ischemic Stroke.Molecular neurobiology · 2024
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Xinyu WangBinzhou Medical University, Laishan District, Yantai, 264003 Shandong, China.ORCID https://orcid.org/0000-0003-0622-5537
Lei YeBinzhou Medical University, Laishan District, Yantai, 264003 Shandong, China.ORCID https://orcid.org/0000-0001-6653-1953
Wanru SunBinzhou Medical University, Laishan District, Yantai, 264003 Shandong, China.ORCID https://orcid.org/0000-0003-4947-5747
Liya LiBinzhou Medical University, Laishan District, Yantai, 264003 Shandong, China.ORCID https://orcid.org/0000-0001-9457-0829
Chaoyun WangBinzhou Medical University, Laishan District, Yantai, 264003 Shandong, China.ORCID https://orcid.org/0000-0003-0578-1160
Xiaoyan XuBinzhou Medical University, Laishan District, Yantai, 264003 Shandong, China.ORCID https://orcid.org/0000-0003-3646-3130
Zhaohai PanBinzhou Medical University, Laishan District, Yantai, 264003 Shandong, China.ORCID https://orcid.org/0000-0002-4822-9248
Jianwei GongBinzhou Medical University, Laishan District, Yantai, 264003 Shandong, China.ORCID https://orcid.org/0000-0002-7294-7194

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dihuang Yinzi, as a classical Chinese medicine prescription, plays an important role for the treatment of ischemic stroke. Gut microbiota play a functional role for the expression of proinflammatory cytokines and anti-inflammatory cytokines, which further affect central nervous system and change brain function. Our research confirmed that Dihuang Yinzi can exert brain protection by inhibiting inflammatory reaction. Dihuang Yinzi can significantly decrease the contents of interleukin-6 (IL-6), tumor necrosis factor-

Indexed as

Brain IschemiaGastrointestinal MicrobiomeIschemic StrokeAnimalsCerebral InfarctionCytokinesInflammationRatsRats, Sprague-DawleyReperfusionRNA, Ribosomal, 16SCytokinesRNA, Ribosomal, 16S

Identifiers

PMID36033571
PMCPMC9402306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.