Evidence map›Paper›PMID 36033560›Full record

ArticleBioMed research international2022

A Nested Case-Control Study of the Relationship between Salivary Inflammatory Mediators, Periodontal Parameters, and Preterm Birth in a Chinese Population.

Min Wu, Chanjuan Ye, Huijun Li, Xiuqiao Yang, Sujun Zhu, Fangming Zhou, Ying Hao, Shaowu Chen, Shaoyun Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Min WuDepartment of Stomatology, The Affiliated Shenzhen Maternity and Child Healthcare Hospital of the South Medical University, Shenzhen 518048, China.ORCID https://orcid.org/0000-0001-6640-5826
Chanjuan YeDepartment of Stomatology, The Affiliated Shenzhen Maternity and Child Healthcare Hospital of the South Medical University, Shenzhen 518048, China.ORCID https://orcid.org/0000-0003-2810-9254
Huijun LiDepartment of Stomatology, The Affiliated Shenzhen Maternity and Child Healthcare Hospital of the South Medical University, Shenzhen 518048, China.ORCID https://orcid.org/0000-0001-9003-1035
Xiuqiao YangDepartment of Stomatology, The Affiliated Shenzhen Maternity and Child Healthcare Hospital of the South Medical University, Shenzhen 518048, China.ORCID https://orcid.org/0000-0003-2869-9610
Sujun ZhuDepartment of Obstetrics and Gynecology, The Affiliated Shenzhen Maternity and Child Healthcare Hospital of the South Medical University, Shenzhen 518048, China.ORCID https://orcid.org/0000-0003-1161-4668
Fangming ZhouClinical Laboratory, The Affiliated Shenzhen Maternity and Child Healthcare Hospital of the South Medical University, Shenzhen 518048, China.ORCID https://orcid.org/0000-0001-7804-1898
Ying HaoClinical Laboratory, The Affiliated Shenzhen Maternity and Child Healthcare Hospital of the South Medical University, Shenzhen 518048, China.ORCID https://orcid.org/0000-0001-7599-5813
Shaowu ChenDepartment of Stomatology, The Affiliated Shenzhen Maternity and Child Healthcare Hospital of the South Medical University, Shenzhen 518048, China.ORCID https://orcid.org/0000-0002-0224-3239
Shaoyun JiangStomatological Center, Peking University Shenzhen Hospital, Guangdong Provincial High-Level Clinical Key Specialty, Guangdong Province Engineering Research Center of Oral Disease Diagnosis and Treatment, Shenzhen 518056, China.ORCID https://orcid.org/0000-0002-4230-1341

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To explore whether salivary inflammatory mediators and periodontal indices at different gestational stages can be taken as indicators of preterm birth (PTB). Methods: This nested case-control study enrolled systemically healthy pregnant women at 9 to 36 weeks of gestation. Periodontal indices were measured at the enrollment date, and interleukin-1 Results: PTB occurred in 26 women. A total of 104 matched women with full-term birth (FTB) were used as controls. The PTB women enrolled at 24-28 gestational weeks displayed a significantly greater bleeding index (BI), probing pocket depth (PD), PD ≥ 4 mm sites (%), saliva-TNF- Conclusions: The combination of BI and PGE2 in saliva at 24-28 gestational weeks could be a predictor of PTB in asymptomatic women. However, the results should be further explored with larger sample size.

Indexed as

Premature Birth8-Hydroxy-2'-DeoxyguanosineCase-Control StudiesChinaDinoprostoneFemaleHumansInfant, NewbornInflammation MediatorsPregnancySalivaTumor Necrosis Factor-alpha8-Hydroxy-2'-DeoxyguanosineDinoprostoneInflammation MediatorsTumor Necrosis Factor-alpha

Identifiers

PMID36033560
PMCPMC9410790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.