Evidence map›Paper›PMID 36033508›Full record

ArticleFrontiers in oncology2022

Automated segmentation of colorectal liver metastasis and liver ablation on contrast-enhanced CT images.

Brian M Anderson, Bastien Rigaud, Yuan-Mao Lin, A Kyle Jones, HynSeon Christine Kang, Bruno C Odisio, Kristy K Brock

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brian M AndersonDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Bastien RigaudDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Yuan-Mao LinDepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
A Kyle JonesDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
HynSeon Christine KangDepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Bruno C OdisioDepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Kristy K BrockDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Funding

Optimization and Evaluation of Anatomical Models of Liver Radiation ResponseR01CA221971 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BROCK, KRISTY · 2018 to 2022
$1.8M
Anatomical Modeling to Improve the Precision of Image Guided Liver AblationR01CA235564 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BROCK, KRISTY, ODISIO, BRUNO C · 2019 to 2023
$1.7M
NCI NIH HHS R01 CA221971NCI NIH HHS R01 CA235564
6 · The paper itself

Abstract

Objectives: Colorectal cancer (CRC), the third most common cancer in the USA, is a leading cause of cancer-related death worldwide. Up to 60% of patients develop liver metastasis (CRLM). Treatments like radiation and ablation therapies require disease segmentation for planning and therapy delivery. For ablation, ablation-zone segmentation is required to evaluate disease coverage. We hypothesize that fully convolutional (FC) neural networks, trained using novel methods, will provide rapid and accurate identification and segmentation of CRLM and ablation zones. Methods: Four FC model styles were investigated: Standard 3D-UNet, Residual 3D-UNet, Dense 3D-UNet, and Hybrid-WNet. Models were trained on 92 patients from the liver tumor segmentation (LiTS) challenge. For the evaluation, we acquired 15 patients from the 3D-IRCADb database, 18 patients from our institution (CRLM = 24, ablation-zone = 19), and those submitted to the LiTS challenge ( Results: The most accurate model was the Hybrid-WNet. On a patient-by-patient basis in the 3D-IRCADb dataset, the median (min-max) Dice similarity coefficient (DSC) was 0.73 (0.41-0.88), the median surface distance was 1.75 mm (0.57-7.63 mm), and the number of false positives was 1 (0-4). In the LiTS challenge ( Conclusion: The Hybrid-WNet model provided fast (<30 s) and accurate segmentations of CRLM and ablation zones on contrast-enhanced CT scans, with positive physician reviews.

Indexed as

biomechanical modelingcomputed tomographydeep-learningliver cancerpercutaneous ablation

Identifiers

PMID36033508
PMCPMC9403767

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.