Evidence map›Paper›PMID 36033469›Full record

ArticleFrontiers in oncology2022

Microwave ablation with local pleural anesthesia for subpleural pulmonary nodules: our experience.

Liangliang Meng, Bin Wu, Xiao Zhang, Xiaobo Zhang, Yingtian Wei, Xiaodong Xue, Zhongliang Zhang, Xin Zhang, Jing Li, Xiaofeng He and 2 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Safety and efficacy of co-ablationJournal of thoracic disease · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Liangliang MengDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Bin WuDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Xiao ZhangDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Xiaobo ZhangDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yingtian WeiDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Xiaodong XueDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Zhongliang ZhangDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Xin ZhangDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Jing LiDepartment of MRI, Affiliated Hospital, Logistics University of Chinese Peoples Armed Police Forces, Tianjin, China.
Xiaofeng HeDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Li MaDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yueyong XiaoDepartment of Radiology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To explore the efficacy and safety of local pleural anesthesia (LPA) for relieving pain during microwave ablation (MWA) of pulmonary nodules in the subpleural regions. Materials and Methods: From June 2019 to December 2021, 88 patients with 97 subpleural nodules underwent percutaneous CT-guided MWA. Patients were divided into two groups according to whether LPA was applied; 53 patients with local pleural anesthesia during MWA; and 35 patients with MWA without LPA. The differences in technical success, pre-and post- and intra-operative visual analog scale (VAS) pain scores, complications of the procedure, and local progression-free survival (LPFS) between the two groups were assessed. Thus, to evaluate the efficacy and safety of MWA combined with LPA for treating subpleural nodules. Results: In this study, the procedures in all patients of both groups achieved technical success according to pre-operative planning. There was no statistically significant difference in the pre-operative VAS pain scores between the two groups. Intra-operative VAS scores were significantly higher in the non-LPA (NLPA) group than in the LPA group. They remained significantly higher in the NLPA group than in the LPA group during the short postoperative period. Analgesics were used more in the NLPA group than in the LPA group intra- and postoperatively, with a statistically significant difference, especially during the MWA procedures. The overall LPFS rates were 100%, 98.333%, 98.333%, and 98.333% at 1, 3, 6, and 12 months postoperatively in the LPA group and 100%, 97.297%, 94.595%, and 94.595% postoperatively in the NLPA group, respectively. Tumor recurrence occurred in one and two patients with lung adenocarcinoma in the LPA and NLPA groups. The incidence of pneumothorax was significantly higher in the NLPA group (25,714%, 9/35) than in the LPA group (15.094%, 8/53), and there were three cases of pleural effusion (blood collection) and one case of pulmonary hemorrhage in the NLPA group. Conclusion: Percutaneous CT-guided MWA is a safe and effective treatment for subpleural pulmonary nodules. Applying a combined LPA technique can reduce the patient's pain and complications during and after the MWA. The long-term efficacy must be verified in more patients and a longer follow-up.

Indexed as

anesthesialung cancermicrowave ablation (MWA)painpleural

Identifiers

PMID36033469
PMCPMC9411023

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