Evidence map›Paper›PMID 36033462›Full record

ArticleFrontiers in oncology2022

Molecular and pathological subtypes related to prostate cancer disparities and disease outcomes in African American and European American patients.

Joakin O Mori, Jason White, Isra Elhussin, Babatunde M Duduyemi, Balasubramanyam Karanam, Clayton Yates, Honghe Wang

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joakin O MoriDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL, United States.
Jason WhiteDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL, United States.
Isra ElhussinDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL, United States.
Babatunde M DuduyemiCollege of Medicine and Allied Health Sciences, University of Sierra Leone Teaching Hospital, Freetown, Sierra Leone.
Balasubramanyam KaranamDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL, United States.
Clayton YatesDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL, United States.
Honghe WangDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) disproportionately affects African American (AA) men, yet present biomarkers do not address the observed racial disparity. The objective of this study was to identify biomarkers with potential benefits to AA PCa patients. Differentially expressed genes (DEG) analysis coupled with gene set enrichment analysis (GSEA) and leading-edge genes analysis showed that the keratin family of genes, including

Indexed as

cancer disparitiesmolecular subtype classificationoncogenic pathwaysprognosisprostate cancer

Identifiers

PMID36033462
PMCPMC9399459

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.