Evidence map›Paper›PMID 36033442›Full record

ArticleFrontiers in oncology2022

Nomogram individually predicts the risk for distant metastasis and prognosis value in female differentiated thyroid cancer patients: A SEER-based study.

Wenlong Wang, Cong Shen, Zhi Yang

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Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Wenlong WangGeneral Surgery Department, Xiangya Hospital, Central South University, Changsha, China.
Cong ShenGeneral Surgery Department, Xiangya Hospital, Central South University, Changsha, China.
Zhi YangNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Distant metastasis (DM) is an important prognostic factor in differentiated thyroid cancer (DTC) and determines the course of treatment. This study aimed to establish a predictive nomogram model that could individually estimate the risk of DM and analyze the prognosis of female DTC patients (FDTCs). Materials and methods: A total of 26,998 FDTCs were retrospectively searched from the Surveillance, Epidemiology, and End Results (SEER) database from 2010 to 2018 and randomly divided into validation and training cohorts. Univariate and multivariate analyses were performed to screen for prognostic factors and construct a prediction nomogram. The performance of the nomogram was assessed by the area under the receiver operating characteristic curve (AUC), concordance index (C-index), and a calibration curve. The overall survival (OS) and cancer-specific survival (CSS) were evaluated by Kaplan-Meier (K-M) analysis. Results: A total of 263 (0.97%) FDTCs were reported to have DM. K-M analysis showed the association of multiple-organ metastases and brain involvement with lower survival rates ( Conclusion: Our study was successful in establishing and validating nomograms that could predict DM, as well as CSS and OS in individual patients with FDTC based on a large study cohort. These nomograms could enable surgeons to perform individualized survival evaluation and risk stratification for FDTCs.

Indexed as

differentiated thyroid cancer (DTC)distant metastasis (DM)nomogramoverall survival (OS)prognosis

Identifiers

PMID36033442
PMCPMC9399418

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