ArticleJournal of immunology research2022
Establishing Reference Values for Peripheral Blood Lymphocyte Subsets of Healthy Children in China Using a Single Platform.
Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Ultrasensitive multiplex salivary cytokine profiling reveals distinct immune signatures in dental caries.BDJ open · 2026Article
- Profound immune suppression and exhaustion characterize refractory mycoplasma pneumoniae pneumonia in children.Frontiers in immunology · 2026Article
- Immune dysregulation and pathogen prevalence in Mycoplasma pneumoniae pneumonia: a retrospective insight in children.Frontiers in pediatrics · 2026Article
- Clinical characteristics and decreased CD4Frontiers in immunology · 2026Article
- Immunological characteristics of children with autism spectrum disorder and comorbid atopic dermatitis.Frontiers in pediatrics · 2026Article
- Preoperative neutrophil-to-lymphocyte ratio as an early risk-stratification and prognostic biomarker in Wilms tumor: a retrospective study.Frontiers in oncology · 2026Article
- [Analysis of antiviral efficacy in pediatric patients with HBeAg-negative chronic hepatitis B].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Article
- Differences in immune function and cytokine levels among children in different age groups with severe community-acquired pneumonia.Scientific reports · 2025Article
- Early-life human CD8Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Decoupled dynamics of absolute and relative lymphocyte counts and age-polarized CD4Frontiers in immunology · 2025Article
- Allergic Disease with Selective IgA Deficiency. Comment on Cinicola et al. The Allergic Phenotype of Children and Adolescents with Selective IgA Deficiency: A Longitudinal Monocentric Study.Journal of clinical medicine · 2023Article
- Psoriasis Area and Severity Index (PASI) Objectivisation by Flow Cytometry Analysis of Major Lymphocytes Subsets.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023Article
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7 authors.
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Abstract
Lymphocyte subsets significantly change during childhood; thus, age-matched reference values derived from healthy children are crucial. We established reference values for lymphocyte subsets, including T cells (CD3+), CD4 T cells (CD3 + CD4+), CD8 T cells (CD3 + CD8+), double negative T (DNT) cells (CD3 + CD4-CD8-), B cells (CD3-CD19+), NK cells (CD3-CD56+), and NKT-like cells (CD3 + CD56+) in the peripheral blood of 813 healthy children. We used the method of the international standard document (Clinical Laboratory Standard Institute C28-A3) to establish reference intervals with a single platform. First, we used the Skewness and Kurtosis test to analyze the normality of the data. The nonnormally distributed data was transformed into approximately normal distribution by the Box-Cox transformation. Second, we used the Tukey's method to eliminate outliers. Further, all the subjects were grouped into subgroups according to sex (male and female) and age (0-1 month, 2-12 months, 1-3 years, 4-6 years, and 7-18 years). We used the standard normal deviation test (
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