Evidence map›Paper›PMID 36033359›Full record

ArticlePhysics of fluids (Woodbury, N.Y. : 1994)2022

Splitting of a three-dimensional liquid plug at an airway bifurcation.

Hideki Fujioka, Francesco Romanò, Metin Muradoglu, James B Grotberg

Abstract read
In one paragraph

Article in Physics of fluids (Woodbury, N.Y. : 1994), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Mechanical ventilation energy analysis: Recruitment focuses injurious power in the ventilated lung.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Splitting of a three-dimensional liquid plug at an airway bifurcation.Physics of fluids (Woodbury, N.Y. : 1994) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hideki FujiokaCenter for Computational Science, Tulane University, 6823 St. Charles Avenue, New Orleans, Louisiana 70118, USA.ORCID https://orcid.org/0000-0001-5947-9667
Francesco RomanòUniv. Lille, CNRS, ONERA, Arts et Métiers Institute of Technology, Centrale Lille, UMR 9014-LMFL-Laboratoire de Mécanique des Fluides de Lille-Kampé de Fériet, F-59000 Lille, France.ORCID https://orcid.org/0000-0002-9511-4718
Metin MuradogluDepartment of Mechanical Engineering, Koc University, Rumelifeneri Yolu Sariyer/Istanbul 34450, Turkey.ORCID https://orcid.org/0000-0002-1758-5418
James B GrotbergDepartment of Biomedical Engineering, University of Michigan, 2200 Bonisteel Blvd., Ann Arbor, Michigan 48109, USA.ORCID https://orcid.org/0000-0001-7917-2451

Funding

Microfluidic Tissue Engineering of Small Airway InjuriesR01HL136141 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI GROTBERG, JAMES BERNARD, NEMZEK, JEAN A · 2017 to 2020
$2.9M
NHLBI NIH HHS R01 HL136141
6 · The paper itself

Abstract

Employing the moving particles' semi-implicit (MPS) method, this study presents a numerical framework for solving the Navier-Stokes equations for the propagation and the split of a liquid plug through a three-dimensional air-filled bifurcating tube, where the inner surface is coated by a thin fluid film, and surface tension acts on the air-liquid interface. The detailed derivation of a modified MPS method to handle the air-liquid interface of liquid plugs is presented. When the front air-liquid interface of the plug splits at the bifurcation, the interface deforms quickly and causes large wall shear stress. We observe that the presence of a transverse gravitational force causes asymmetries in plug splitting, which becomes more pronounced as the capillary number decreases or the Bond number increases. We also observe that there exists a critical capillary number below which the plug does not split into two daughter tubes but propagates into the lower daughter tube only. In order to deliver the plug into the upper daughter tube, the driving pressure to push the plug is required to overcome the hydrostatic pressure due to gravity. These tendencies agree with our previous experimental and theoretical studies.

Identifiers

PMID36033359
PMCPMC9406020

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.