Evidence map›Paper›PMID 36033314›Full record

ArticleHeliyon2022

Degradation of ciprofloxacin in aqueous solution using ozone microbubbles: spectroscopic, kinetics, and antibacterial analysis.

Sera Budi Verinda, Muflihatul Muniroh, Eko Yulianto, Nani Maharani, Gunawan Gunawan, Nur Farida Amalia, Jonathan Hobley, Anwar Usman, Muhammad Nur

Abstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sera Budi VerindaBiomedical Graduate Program, Faculty of Medicine, Universitas Diponegoro, Tembalang, Semarang 50275, Indonesia.
Muflihatul MunirohDepartment of Physiology, Faculty of Medicine, Universitas Diponegoro, Tembalang, Semarang 50275, Indonesia.
Eko YuliantoCenter for Plasma Research, Integrated Laboratory, Universitas Diponegoro, Tembalang, Semarang 50275, Indonesia.
Nani MaharaniDepartment of Pharmacology and Therapy, Faculty of Medicine, Universitas Diponegoro, Tembalang, Semarang 50275, Indonesia.
Gunawan GunawanDepartment of Chemistry, Faculty of Science and Mathematics, Universitas Diponegoro, Tembalang, Semarang 50275, Indonesia.
Nur Farida AmaliaDepartment of Physics, Faculty of Science and Mathematics, Universitas Diponegoro, Tembalang, Semarang 50275, Indonesia.
Jonathan HobleyDepartment of Biomedical Engineering, National Cheng Kung University, No. 1 University Road, Tainan City 701, Taiwan.
Anwar UsmanDepartment of Chemistry, Faculty of Science, Universiti Brunei Darussalam, Jalan Tungku Link, Gadong BE1410, Brunei.
Muhammad NurCenter for Plasma Research, Integrated Laboratory, Universitas Diponegoro, Tembalang, Semarang 50275, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ciprofloxacin (CIP) has been listed in the last version of the surface water due to its ability to kill human cells by inhibiting the activity of DNA topoisomerase IV. Thus, CIP, along with other antibiotic pollution has become a serious threat to the environment and public health. Ozonation has been used as an advanced technique that is applied in wastewater treatment to remove CIP, but the primary limitation of this method is the low solubility of ozone in water. This study is the first report of CIP removal in a scale-up of its aqueous solution using a self-developed aerator pump-enhanced ozonation (APO) system, which only employs a propeller and a zigzag arrangement of meshes. This aerator pump decreased the size of ozone bubbles by 90% and increased the effective ozone solubility to 0.47 ppm. The mechanism of degradation of CIP is attributed to an oxidation reaction of the antibiotic with reactive oxygen species, such as hydroxyl, oxygen, and hydroperoxyl radicals, generated on the surface of the ozone microbubbles. It was found that the rate and efficiency of degradation of CIP using the APO system were 3.64 × 10

Indexed as

Antibiotic contaminantsCiprofloxacinDegradationMicrobubblesOzone

Identifiers

PMID36033314
PMCPMC9399964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.