ArticleACS central science2022
Tuning Single-Polymer Growth via Hydrogen Bonding in Conformational Entanglements.
Article in ACS central science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Molecule by Molecule Characterization of a Polymer Molecular Mass Distribution via Mass Photometry.Angewandte Chemie (International ed. in English) · 2026Article
- Biphasic mechanochemistry of single-chain polymerization.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- From Molecules to Classrooms: A Comprehensive Guide to Single-Molecule Localization Microscopy.Journal of chemical education · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic polymers have widespread applications in daily life and advanced materials applications. Making polymers efficiently and controllably is highly desired, for which modulating intramolecular and intermolecular interactions have been an effective approach. Recent real-time single-polymer growth studies uncovered nonequilibrium conformational entanglements that form stochastically under living polymerization conditions and which appear to plausibly play key roles in controlling the polymerization kinetics and dispersion. Here, using magnetic tweezers measurements, we study the real-time polymerization dynamics of single polynorbornene-based polymers in which we systematically tune the hydrogen-bonding interactions by titrating the OH content in the monomers and the formed polymers during ring opening metathesis polymerization. Using norbornenes with and without a hydroxyl group and a nonreactive monomer analogue, we show that intrachain and intermolecular hydrogen bonding compete, and both alter the microscopic properties of the nonequilibrium entanglements, leading to surprising multiphasic dependences of polymerization dynamics on the polymer's OH content. We further formulate a simple model to rationalize quantitatively the observed multiphasic behaviors by considering the different scaling relations of intrachain and intermolecular hydrogen bonding on the OH content. These results provide insights into the interconnected roles of intra-/intermolecular interactions, polymer chain conformations, and free monomers in solution in affecting polymerization kinetics and dispersion, and point to new opportunities in manipulating polymerization reactions.
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Registered trials
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