Evidence map›Paper›PMID 36032738›Full record

ArticleIranian journal of parasitology

Immunoinformatics Evaluation of a Fusion Protein Composed of

Shima Fayaz, Fariborz Bahrami, Pezhman Fard-Esfahani, Parviz Parvizi, Golnaz Bahramali, Soheila Ajdary

Abstract read
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shima FayazDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Fariborz BahramiDepartment of Immunology, Pasteur Institute of Iran, Tehran, Iran.
Pezhman Fard-EsfahaniDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Parviz ParviziDepartment of Parasitology, Pasteur Institute of Iran, Tehran, Iran.
Golnaz BahramaliDepartment of AIDS and Bloodborne Diseases, Pasteur Institute of Iran, Tehran, Iran.
Soheila AjdaryDepartment of Immunology, Pasteur Institute of Iran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Visceral leishmaniasis (VL) is a lethal parasitic disease, transmitted by sand fly vectors. Immunomodulatory properties of sand fly saliva proteins and their protective effects against Methods: Three different fusion forms of Results: Highly antigenic promiscuous epitopes consisting of truncated LiHyV (10-285) and full-length PkanAp (21-329) were identified in human and was named Model 1. This model contained 25 MHC-I and 141 MHC-II antigenic peptides which among them, MPANSDIRI and AQSLFDFSGLALDSN were fully conserved. LALDSNATV, RCSSALVSI, ALVSINVPL, SAVESGALF of MHC-I epitopes, and 28 MHC-II binding epitopes showed 60% conservancy among various clades. A population coverage with a rate of >75% in the Iranian population and >70% in the whole world was also identified. Conclusion: Based on this

Indexed as

ApyraseImmunoinformaticsLeishmania infantumPhlebotomus kandelakiiVaccine

Identifiers

PMID36032738
PMCPMC9363246

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.