Evidence map›Paper›PMID 36032713›Full record

ReviewFrontiers in bioengineering and biotechnology2022

Medical high-entropy alloy: Outstanding mechanical properties and superb biological compatibility.

Changxi Liu, Chengliang Yang, Jia Liu, Yujin Tang, Zhengjie Lin, Long Li, Hai Liang, Weijie Lu, Liqiang Wang

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. TaMoNbTiZr Multielement Alloy for Medical Instruments.Materials (Basel, Switzerland) · 2025
    Article
  3. Effect of Vanadium Addition on the Wear Resistance of AlMaterials (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Changxi LiuState Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.
Chengliang YangNational Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jia LiuNational Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yujin TangNational Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhengjie Lin3D Printing Clinical Translational and Regenerative Medicine Center, Shenzhen Shekou People's Hospital, Shenzhen, China.
Long LiDepartment of Stomatology, Shenzhen Shekou People's Hospital, Shenzhen, China.
Hai LiangDepartment of Stomatology, Shenzhen Shekou People's Hospital, Shenzhen, China.
Weijie LuState Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.
Liqiang WangState Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical metal implants are required to have excellent mechanical properties and high biocompatibility to handle the complex human environment, which is a challenge that has always existed for traditional medical metal materials. Compared to traditional medical alloys, high entropy alloys (HEAs) have a higher design freedom to allow them to carry more medical abilities to suit the human service environment, such as low elastic modulus, high biocompatible elements, potential shape memory capability. In recent years, many studies have pointed out that bio-HEAs, as an emerging medical alloy, has reached or even surpassed traditional medical alloys in various medical properties. In this review, we summarized the recent reports on novel bio-HEAs for medical implants and divide them into two groups according the properties, namely mechanical properties and biocompatibility. These new bio-HEAs are considered hallmarks of a historic shift representative of a new medical revolution.

Indexed as

bio-heascorrosion resistancecytocompatibilityfriction resistancemechanical properties

Identifiers

PMID36032713
PMCPMC9403318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.