Evidence map›Paper›PMID 36032705›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Encapsulated vaterite-calcite CaCO

Lu Fan, Fabian Körte, Alexander Rudt, Ole Jung, Claus Burkhardt, Mike Barbeck, Xin Xiong

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Biphasic bone substitutes coated with PLGA incorporating therapeutic ions SrFrontiers in bioengineering and biotechnology · 2024
    Article
  4. Article
  5. The Use of Collagen-Based Materials in Bone Tissue Engineering.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lu FanNMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.
Fabian KörteNMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.
Alexander RudtFaculty of Applied Chemistry, Reutlingen University, Reutlingen, Germany.
Ole JungMedical Center of Rostock University, Rostock, Germany.
Claus BurkhardtNMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.
Mike BarbeckMedical Center of Rostock University, Rostock, Germany.
Xin XiongNMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioactive cations, including calcium, copper and magnesium, have shown the potential to become the alternative to protein growth factor-based therapeutics for bone healing. Ion substitutions are less costly, more stable, and more effective at low concentrations. Although they have been shown to be effective in providing bone grafts with more biological functions, the precise control of ion release kinetics is still a challenge. Moreover, the synergistic effect of three or more metal ions on bone regeneration has rarely been studied. In this study, vaterite-calcite CaCO

Indexed as

bioactive cationsbone regenerationcollagenpolyelectrolyte multilayervaterite-calcite

Identifiers

PMID36032705
PMCPMC9403055

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.