Evidence map›Paper›PMID 36032692›Full record

ArticleNeuroimage. Reports2022

Test-retest reliability of FreeSurfer-derived volume, area and cortical thickness from MPRAGE and MP2RAGE brain MRI images.

Graham N Knussmann, Jeffrey S Anderson, Molly B D Prigge, Douglas C Dean, Nicholas Lange, Erin D Bigler, Andrew L Alexander, Janet E Lainhart, Brandon A Zielinski, Jace B King

Open access · goldAbstract read
In one paragraph

Article in Neuroimage. Reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Graham N KnussmannDepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
Jeffrey S AndersonDepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
Molly B D PriggeDepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
Douglas C DeanWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Nicholas LangeDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Erin D BiglerDepartment of Psychology and Neuroscience Center, Brigham Young University, Provo, UT, USA.
Andrew L AlexanderWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Janet E LainhartWaisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Brandon A ZielinskiDepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
Jace B KingDepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
University of Utah · USUniversity of Wisconsin–Madison · USBrigham Young University · USHarvard University · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Atypical Late Neurodevelopment in Autism: A Longitudinal MRI and DTI StudyR01MH080826 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI LAINHART, JANET ELIZABETH · 2007 to 2020
$6.5M
Siemens MAGNETOM Vida 3T MRI ScannerS10OD026788 · OD · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 2019 to 2019
$2.0M
Siemens MAGNETOM Prisma 3T MRI scannerS10OD018482 · OD · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 2015 to 2015
$1.2M
Brain Network Development in Normal and Autistic ChildrenK08MH100609 · NIMH · UNIVERSITY OF UTAH · PI ZIELINSKI, BRANDON A. · 2014 to 2017
$759k
NCATS NIH HHS UL1 TR002538NIH HHS S10 OD018482NIH HHS S10 OD026788NIMH NIH HHS K08 MH100609NIMH NIH HHS R01 MH080826
6 · The paper itself

Abstract

Background and purpose: Large MRI studies often pool data gathered from widely varying imaging sequences. Pooled data creates a potential source of variation in structural analyses which may cause misinterpretation of findings. The purpose of this study is to determine if data acquired using different scan sequences, head coils and scanners offers consistent structural measurements. Materials and methods: Participants (163 right-handed males: 82 typically developing controls, 81 participants with autism spectrum disorder) were scanned on the same day using an MPRAGE sequence with a 12-channel headcoil on a Siemens 3T Trio scanner and an MP2RAGE sequence with a 64-channel headcoil on a Siemens 3T Prisma scanner. Segmentation was performed using FreeSurfer to identify regions exhibiting variation between sequences on measures of volume, surface area, and cortical thickness. Intraclass correlation coefficient (ICC) and mean percent difference (MPD) were used as test-retest reproducibility measures. Results: ICC for total brain segmented volume yielded a 0.99 intraclass correlation, demonstrating high overall volumetric reproducibility. Comparison of individual regions of interest resulted in greater variation. Volumetric variability, although low overall, was greatest in the entorhinal cortex (ICC = 0.71), frontal (ICC = 0.60) and temporal (ICC = 0.60) poles. Surface area variability was greatest in the insula (ICC = 0.65), temporal (ICC = 0.64) and frontal (ICC = 0.68) poles. Cortical thickness was most variable in the frontal (ICC = 0.41) and temporal (ICC = 0.35) poles. Conclusion: Data collected on different scanners and head coils using MPRAGE and MP2RAGE are generally consistent for surface area and volume estimates. However, regional variability may constrain accuracy in some regions and cortical thickness measurements exhibit higher generalized variability.

Indexed as

FreeSurferMP2RAGEMPRAGEReliability

Identifiers

PMID36032692
PMCPMC9409374
OpenAlexW4214563890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.