Evidence map›Paper›PMID 36032591›Full record

ArticleMaedica2022

Sarcopenia in Urinary Bladder Cancer: Definition, Prevalence and Prognostic Value in Survival.

Themistoklis Ch Bellos, Lazaros I Tzelves, Ioannis S Manolitsis, Stamatios N Katsimperis, Marinos V Berdempes, Andreas Skolarikos, Nikolaos D Karakousis

Abstract readEditorial
In one paragraph

Article in Maedica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Themistoklis Ch Bellos2nd Department of Urology, Sismanoglio General Hospital of Athens, Athens, Greece.
Lazaros I Tzelves2nd Department of Urology, Sismanoglio General Hospital of Athens, Athens, Greece.
Ioannis S Manolitsis2nd Department of Urology, Sismanoglio General Hospital of Athens, Athens, Greece.
Stamatios N Katsimperis2nd Department of Urology, Sismanoglio General Hospital of Athens, Athens, Greece.
Marinos V Berdempes2nd Department of Urology, Sismanoglio General Hospital of Athens, Athens, Greece.
Andreas Skolarikos2nd Department of Urology, Sismanoglio General Hospital of Athens, Athens, Greece.
Nikolaos D KarakousisPrimary Healthcare, Internal Medicine Department, Amarousion, Attica, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia, defined as the systemic loss of muscle function and mass, is commonly seen in advanced oncologic states, usually in conjunction with cancer cachexia. Bladder cancer represents one of the most common neoplasms worldwide and affects mainly the elderly who are already frail. The purpose of this study is to review the potential association between sarcopenia and bladder cancer in patients receiving different types of treatments. A thorough MEDLINE/PubMed non-systematic literature review was conducted from 1990 to January 2022, using the following search terms: "sarcopenia and bladder cancer" and "low muscle mass and bladder cancer". Sarcopenia probably poses a negative impact on the prognosis of patients at any stage of bladder cancer, as it is linked with overall worse survival, cancer specific survival and progression-free survival in those treated, with either radical cystectomy or chemotherapy. In addition, sarcopenia seems to be a strong predictor concerning complications and a negative prognostic factor following chemotherapy and surgery for bladder cancer. On the other hand, it seems that sarcopenic patients who receive radiotherapy or immunotherapy are not so severely affected.

Identifiers

PMID36032591
PMCPMC9375863

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.