ArticleBiomedical optics express2022
Depth-resolved visualization and automated quantification of hyperreflective foci on OCT scans using optical attenuation coefficients.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
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Who cites it
20 citing papers in PubMed.
- Novel Clinical Trial Designs for Intermediate Age-Related Macular Degeneration.Ophthalmology science · 2026Article
- U-Net Optimization for Hyperreflective Foci Segmentation in Retinal OCT.Diagnostics (Basel, Switzerland) · 2026Article
- Depth-Resolved Attenuation Coefficient Quantification During Murine Embryonic Brain Development.Journal of biophotonics · 2025Article
- Quantitative assessment of retinal attenuation and backscattering in OCT imaging using iterative layer-based analysis.Biomedical optics express · 2025Article
- Hyperreflective Foci Along the Retinal Pigment Epithelium Predict the Onset of Large Choroidal Hypertransmission Defects in Age-Related Macular Degeneration.American journal of ophthalmology · 2025Article
- Three-dimensional C-scan-based generation adversarial network with synthetic input to improve optical coherence tomography angiography.Journal of biomedical optics · 2025Article
- Photoreceptor Function and Structure in Retinal Areas With Intraretinal Hyperreflective Foci in Age-Related Macular Degeneration.Investigative ophthalmology & visual science · 2025Article
- A Novel Grid Strategy for Correlating Focal Macular Anatomic Changes With Focal Changes in Choriocapillaris Perfusion.Investigative ophthalmology & visual science · 2024Article
- The Total Macular Burden of Hyperreflective Foci and the Onset of Persistent Choroidal Hypertransmission Defects in Intermediate AMD.American journal of ophthalmology · 2024Article
- A new texture-based labeling framework for hyper-reflective foci identification in retinal optical coherence tomography images.Scientific reports · 2024Article
- iStent insertion orientation and impact on trabecular meshwork motion resolved by optical coherence tomography imaging.Journal of biomedical optics · 2024Article
- Calcified Drusen Prevent the Detection of Underlying Choriocapillaris Using Swept-Source Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2024Article
- Deep-learning-based automated measurement of outer retinal layer thickness for use in the assessment of age-related macular degeneration, applicable to both swept-source and spectral-domain OCT imaging.Biomedical optics express · 2024Article
- Unleashing the power of optical attenuation coefficients to facilitate segmentation strategies in OCT imaging of age-related macular degeneration: perspective.Biomedical optics express · 2023Article
- Deep learning segmentation of the tear fluid reservoir under the sclera lens in optical coherence tomography images.Biomedical optics express · 2023Article
- Automated segmentation and quantification of calcified drusen in 3D swept source OCT imaging.Biomedical optics express · 2023Article
- Integrating a pressure sensor with an OCT handheld probe to facilitate imaging of microvascular information in skin tissue beds.Biomedical optics express · 2022Article
- Comparison between Spectral-Domain and Swept-Source OCT Angiography for the Measurement of Persistent Hypertransmission Defects in Age-Related Macular Degeneration.Ophthalmology scienceArticle
- Comparison between Spectral-domain and Swept-source OCT Angiography Scans for the Measurement of Hyperreflective Foci in Age-related Macular Degeneration.Ophthalmology scienceArticle
- Spectral-Domain and Swept-Source OCT Angiographic Scans Yield Similar Drusen Measurements When Processed with the Same Algorithm.Ophthalmology scienceArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
An automated depth-resolved algorithm using optical attenuation coefficients (OACs) was developed to visualize, localize, and quantify hyperreflective foci (HRF) seen on OCT imaging that are associated with macular hyperpigmentation and represent an increased risk of disease progression in age related macular degeneration. To achieve this, we first transformed the OCT scans to linear representation, which were then contrasted by OACs. HRF were visualized and localized within the entire scan by differentiating HRF within the retina from HRF along the retinal pigment epithelium (RPE). The total pigment burden was quantified using the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.