ArticleBiomedical optics express2022
Intergrader agreement of foveal cone topography measured using adaptive optics scanning light ophthalmoscopy.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed.
- The relationship between foveal anatomy and retinal function in oculocutaneous albinism.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- Assessing the Relationship between Foveal Cone Density, Outer Nuclear Layer Thickness and Foveal Morphology.Ophthalmology science · 2026Article
- In Vivo Cone Photoreceptor Topography of the Human Foveola.Investigative ophthalmology & visual science · 2025Article
- Neural network assisted annotation and analysis tool to study in-vivo foveolar cone photoreceptor topography.Scientific reports · 2025Article
- Article
- Intervisit Reproducibility of Foveal Cone Density Metrics.Translational vision science & technology · 2024Article
- FOVEAL PHENOTYPES IN CHOROIDEREMIA ON ADAPTIVE OPTICS SCANNING LIGHT OPHTHALMOSCOPY.Retina (Philadelphia, Pa.) · 2024Article
- Peak Cone Density Predicted from Outer Segment Length Measured on Optical Coherence Tomography.Current eye research · 2024Article
- The effect of sampling window size on topographical maps of foveal cone density.Frontiers in ophthalmology · 2024Article
- Cone Density Is Correlated to Outer Segment Length and Retinal Thickness in the Human Foveola.Investigative ophthalmology & visual science · 2023Article
- Macular and Plasma Xanthophylls Are Higher in Age-related Macular Degeneration than in Normal Aging: Alabama Study on Early Age-related Macular Degeneration 2 Baseline.Ophthalmology science · 2023Article
- Introduction to the Feature Issue on Adaptive Optics for Biomedical Applications.Biomedical optics express · 2023Article
- Foveal Cone Structure in Patients With Blue Cone Monochromacy.Investigative ophthalmology & visual science · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
The foveal cone mosaic can be directly visualized using adaptive optics scanning light ophthalmoscopy (AOSLO). Previous studies in individuals with normal vision report wide variability in the topography of the foveal cone mosaic, especially the value of peak cone density (PCD). While these studies often involve a human grader, there have been no studies examining intergrader reproducibility of foveal cone mosaic metrics. Here we re-analyzed published AOSLO foveal cone images from 44 individuals to assess the relationship between the cone density centroid (CDC) location and the location of PCD. Across 5 graders with variable experience, we found a measurement error of 11.7% in PCD estimates and higher intergrader reproducibility of CDC location compared to PCD location (p < 0.0001). These estimates of measurement error can be used in future studies of the foveal cone mosaic, and our results support use of the CDC location as a more reproducible anchor for cross-modality analyses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.