Evidence map›Paper›PMID 36032566›Full record

ArticleBiomedical optics express2022

Ultrathin, high-speed, all-optical photoacoustic endomicroscopy probe for guiding minimally invasive surgery.

Tianrui Zhao, Truc Thuy Pham, Christian Baker, Michelle T Ma, Sebastien Ourselin, Tom Vercauteren, Edward Zhang, Paul C Beard, Wenfeng Xia

Abstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Photoacoustic imaging plus X: a review.Journal of biomedical optics · 2024
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tianrui ZhaoSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4 Floor, Lambeth Wing St Thomas' Hospital, London SE1 7EH, United Kingdom.
Truc Thuy PhamSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4 Floor, Lambeth Wing St Thomas' Hospital, London SE1 7EH, United Kingdom.
Christian BakerSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4 Floor, Lambeth Wing St Thomas' Hospital, London SE1 7EH, United Kingdom.
Michelle T MaSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4 Floor, Lambeth Wing St Thomas' Hospital, London SE1 7EH, United Kingdom.
Sebastien OurselinSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4 Floor, Lambeth Wing St Thomas' Hospital, London SE1 7EH, United Kingdom.
Tom VercauterenSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4 Floor, Lambeth Wing St Thomas' Hospital, London SE1 7EH, United Kingdom.
Edward ZhangDepartment of Medical Physics and Biomedical Engineering, University College London, Gower Street, London WC1E 6BT, UK.
Paul C BeardDepartment of Medical Physics and Biomedical Engineering, University College London, Gower Street, London WC1E 6BT, UK.
Wenfeng XiaSchool of Biomedical Engineering and Imaging Sciences, King's College London, 4 Floor, Lambeth Wing St Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID https://orcid.org/0000-0002-1147-6886

Funding

Wellcome Trust
6 · The paper itself

Abstract

Photoacoustic (PA) endoscopy has shown significant potential for clinical diagnosis and surgical guidance. Multimode fibres (MMFs) are becoming increasingly attractive for the development of miniature endoscopy probes owing to their ultrathin size, low cost and diffraction-limited spatial resolution enabled by wavefront shaping. However, current MMF-based PA endomicroscopy probes are either limited by a bulky ultrasound detector or a low imaging speed that hindered their usability. In this work, we report the development of a highly miniaturised and high-speed PA endomicroscopy probe that is integrated within the cannula of a 20 gauge medical needle. This probe comprises a MMF for delivering the PA excitation light and a single-mode optical fibre with a plano-concave microresonator for ultrasound detection. Wavefront shaping with a digital micromirror device enabled rapid raster-scanning of a focused light spot at the distal end of the MMF for tissue interrogation. High-resolution PA imaging of mouse red blood cells covering an area 100

Identifiers

PMID36032566
PMCPMC9408236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.