Evidence map›Paper›PMID 36032564›Full record

ArticleBiomedical optics express2022

Depth-resolved extraction of optical attenuation for glaucoma assessment in clinical settings: a pilot study.

Shuang Chang, Clara Murff, Theodore Leng, Sylvia L Groth, Audrey K Bowden

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuang ChangVanderbilt University, Vanderbilt Biophotonics Center, Department of Biomedical Engineering, Nashville, TN 37232, USA.
Clara MurffVanderbilt University, Vanderbilt Biophotonics Center, Department of Biomedical Engineering, Nashville, TN 37232, USA.
Theodore LengByers Eye Institute at Stanford, Stanford School of Medicine, Palo Alto, CA 94303, USA.
Sylvia L GrothVanderbilt Eye Institute, Vanderbilt University Medical Center, Department of Ophthalmology and Visual Sciences, Nashville, TN 37232, USA.
Audrey K BowdenVanderbilt University, Vanderbilt Biophotonics Center, Department of Biomedical Engineering, Nashville, TN 37232, USA.

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

We assessed the ability of the optical attenuation coefficient (AC) to detect early-stage glaucoma with two AC estimation algorithms: retinal layer intensity ratio (LIR) and depth-resolved confocal (DRC). We also introduced new depth-dependent AC parameters for retinal nerve fiber layer assessment. Optical coherence tomography B-scans were collected from 44 eyes of age-similar participants with eye health ranging from healthy to severe glaucoma, including glaucoma suspect patients. Mean AC values estimated from the DRC method are comparable to ratio-extracted values (

Identifiers

PMID36032564
PMCPMC9408251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.