ArticleAfrican health sciences2022
In vitro antioxidant and cytotoxicity activities of selected indigenous South African medicinal plants.
Article in African health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Exploring the medicinal potential of Bulbine latifolia (L.f.) Spreng.: a comprehensive review of phytochemicals and therapeutic applications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Sexual reproductive health, NCDs and infectious diseases.African health sciences · 2022Article
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Authors and funding
3 authors.
Funding
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Abstract
Background: Medicinal plants are regarded as a large source of phytochemicals that may have anticancer properties. This could lead to the development of innovative drugs or alternative therapy against cancer. Objective: This study was designed to determine the antioxidant and cytotoxicity effect of 5 selected indigenous South African medicinal plants namely; Method: Phytochemical extracts namely; methanol, 50%, 100% ethanol, and water extracts were prepared from the root and shoot of the plants. The antioxidant effect of methanol extracts of the plant materials was performed using a DPPH assay. A preliminary cytotoxicity screening of the phytochemical extracts in the human colon (Caco-2), cervical (HeLa), and hepatocellular (HepG2) cell lines were determined followed by the half-maximal inhibitory concentration (IC50) using MTT assay. Result: The methanol root extract of Conclusion:
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