Evidence map›Paper›PMID 36032440›Full record

ArticleAfrican health sciences2022

Neurological disorders in Northern Tanzania: A 6-year prospective hospital-based case series.

William P Howlett, Sarah J Urasa, Venance P Maro, Richard W Walker, Kajiru G Kilonzo, Patrick J Howlett, Marieke Cj Dekker

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Article in African health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

William P HowlettKilimanjaro Christian Medical Centre, Moshi, Kilimanjaro, Tanzania.
Sarah J UrasaKilimanjaro Christian Medical Centre, Moshi, Kilimanjaro, Tanzania.
Venance P MaroKilimanjaro Christian Medical Centre, Moshi, Kilimanjaro, Tanzania.
Richard W WalkerDepartment of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, Tyne, and Wear NE29 8NH.
Kajiru G KilonzoKilimanjaro Christian Medical Centre, Moshi, Kilimanjaro, Tanzania.
Patrick J HowlettRoyal Brompton and Harefield Hospital Trust Fulham Road, London, SW3 6HP.
Marieke Cj DekkerKilimanjaro Christian Medical Centre, Moshi, Kilimanjaro, Tanzania.
Kilimanjaro Christian Medical Centre · TZNorth Tyneside General Hospital · GBRoyal Brompton Hospital · GBUniversity of Bergen · NO

Funding

Medical Research Council MR/W024861/1
6 · The paper itself

Abstract

Background: The burden of neurological disorders is large and altered by the HIV epidemic. Objectives: We describe the pattern of neurological disorders and their association with HIV infection in adult patients attending a consultant hospital in Northern Tanzania. Methods: In this prospective cross-sectional study, we collected data on adult neurological referrals over a 6-year period between 2007-13. The odds of HIV infection, across neurological categories adjusted for age and sex, was calculated. Results: Of 2037 participants, 54.8% were male and 45.2% were female. The median age of participants was 43 years. The results for HIV screening were available for 992/2037 (48.7%) patients, of whom 306 (30.8%) were seropositive. The most frequent neurological disorders were cerebrovascular disease (19.9%), paraplegia (13.6%), and peripheral neuropathies (8%). Taken together CNS infection accounted for 278/2037 (13.6%). The adjusted odds (aOR) of HIV infection was highest amongst infections; brain abscesses (aOR 107, 95% CI 35.1-470.4) and meningitis/encephalitis (aOR 40.1, 95% CI 13.6-172.9), but also raised in cerebrovascular disease, paraplegia, peripheral neuropathies, cranial nerve palsies, seizures, cerebllar disorders, movement disorders, motor neuron disease and headache. Conclusion: The main pattern of neurological disorders in Northern Tanzania is presented. The odds of HIV infection was highest in CNS infections and in a wide range of non-communicable neurological disorders.

Indexed as

Cerebrovascular DisordersHIV InfectionsNervous System DiseasesPeripheral Nervous System DiseasesAdultCross-Sectional StudiesFemaleHospitalsHumansMaleParaplegiaPrevalenceProspective StudiesTanzaniadisorderHIVhospitalneurologicalneurological diseaseTanzania

Identifiers

PMID36032440
PMCPMC9382522
OpenAlexW4229370271

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.