Evidence map›Paper›PMID 36032416›Full record

ReviewCurrent research in immunology2022

NMR spectroscopy spotlighting immunogenicity induced by COVID-19 vaccination to mitigate future health concerns.

Sher Ali, Štěpánka Nedvědová, Gul Badshah, Muhammad S Afridi, Abdullah, Lívia M Dutra, Umar Ali, Samara G Faria, Frederico L F Soares, Rafi U Rahman and 6 more

Abstract readReview
In one paragraph

Review in Current research in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. How does NMR support SARS-CoV-2 protein-ligand interaction studies?Analytical and bioanalytical chemistry · 2026
    Review
  2. SARS-CoV2 variants differentially impact on the plasma metabolome.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  3. Whole Mitochondrial DNA Sequencing Using Fecal Samples from Domestic Dogs.Animals : an open access journal from MDPI · 2024
    Article
  4. NMR-Metabolomics in COVID-19 Research.Advances in experimental medicine and biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sher AliDepartment of Chemistry, Federal University of Paraná, CEP 81530-900, Curitiba, PR, Brazil.
Štěpánka NedvědováDepartment of Chemistry, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, Kamýcká 129, 165 00, Praha-Suchdol, Prague, Czech Republic.
Gul BadshahDepartment of Chemistry, Federal University of Paraná, CEP 81530-900, Curitiba, PR, Brazil.
Muhammad S AfridiDepartment of Plant Pathology, Federal University of Lavras, Lavras, Brazil.
AbdullahDepartment of Health and Biological Sciences, Abasyn University Peshawar, CEP 25000, Peshawar, Pakistan.
Lívia M DutraCenter for Studies and Research of Medicinal Plants, Federal University of San Francisco Valley, CEP 56304-205, Petrolina, Brazil.
Umar AliDepartment of Physics and Chemistry, University of Malakand, CEP 18800, Dir (L), Malakand, Pakistan.
Samara G FariaDepartment of Chemistry, Federal University of Paraná, CEP 81530-900, Curitiba, PR, Brazil.
Frederico L F SoaresDepartment of Chemistry, Federal University of Paraná, CEP 81530-900, Curitiba, PR, Brazil.
Rafi U RahmanLaboratory of Physiology and Control of Arthropod Vectors, IOC, Fiocruz, CEP 21040-900, RJ, Brazil.
Fernando A C Q CançadoDepartment of Basic Science, Faculty of Animal Science and Food Engineering, University of São Paulo, CEP 13635-900, Pirassununga, SP, Brazil.
Micheli M C C AoyanagiDepartment of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, CEP13635-900, Pirassununga, SP, Brazil.
Lucas G D FreireDepartment of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, CEP13635-900, Pirassununga, SP, Brazil.
Alan D C SantosDepartment of Chemistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Andersson BarisonDepartment of Chemistry, Federal University of Paraná, CEP 81530-900, Curitiba, PR, Brazil.
Carlos A F OliveiraDepartment of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, CEP13635-900, Pirassununga, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, the disease and immunogenicity affected by COVID-19 vaccination at the metabolic level are described considering the use of nuclear magnetic resonance (NMR) spectroscopy for the analysis of different biological samples. Consistently, we explain how different biomarkers can be examined in the saliva, blood plasma/serum, bronchoalveolar-lavage fluid (BALF), semen, feces, urine, cerebrospinal fluid (CSF) and breast milk. For example, the proposed approach for the given samples can allow one to detect molecular biomarkers that can be relevant to disease and/or vaccine interference in a system metabolome. The analysis of the given biomaterials by NMR often produces complex chemical data which can be elucidated by multivariate statistical tools, such as PCA and PLS-DA/OPLS-DA methods. Moreover, this approach may aid to improve strategies that can be helpful in disease control and treatment management in the future.

Indexed as

ChemometricsCOVID-19ImmunogenicityNuclear magnetic resonance spectroscopyVaccination

Identifiers

PMID36032416
PMCPMC9393187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.