Cardiac Diffusion Tensor Biomarkers of Chronic Infarction Based on In Vivo Data.

Tanjib Rahman, Kévin Moulin, Luigi E Perotti

Open access · goldAbstract read

In one paragraph

Article in Applied sciences (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.4field-weighted citation impact, top 41% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Tanjib RahmanDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0001-8777-1542

Kévin MoulinCREATIS Laboratory, Univ. Lyon, UJM-Saint-Etienne, INSA, CNRS UMR 5520, INSERM, 69100 Villeurbanne, France.ORCID 0000-0002-9188-6403

Luigi E PerottiDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0002-9010-2144

University of Central Florida · USUniversité Claude Bernard Lyon 1 · FR

Funding

Defining and Measuring Diastolic Myocardial Kinematics and StiffnessK25HL135408 · NHLBI · UNIVERSITY OF CENTRAL FLORIDA · PI PEROTTI, LUIGI EMANUELE · 2017 to 2019

$494k

NHLBI NIH HHS K25 HL135408

6 · The paper itself

Abstract

In vivo cardiac diffusion tensor imaging (cDTI) data were acquired in swine subjects six to ten weeks post-myocardial infarction (MI) to identify microstructural-based biomarkers of MI. Diffusion tensor invariants, diffusion tensor eigenvalues, and radial diffusivity (RD) are evaluated in the infarct, border, and remote myocardium, and compared with extracellular volume fraction (ECV) and native T1 values. Additionally, to aid the interpretation of the experimental results, the diffusion of water molecules was numerically simulated as a function of ECV. Finally, findings based on in vivo measures were confirmed using higher-resolution and higher signal-to-noise data acquired ex vivo in the same subjects. Mean diffusivity, diffusion tensor eigenvalues, and RD increased in the infarct and border regions compared to remote myocardium, while fractional anisotropy decreased. Secondary (e

Indexed as

cardiac microstructurechronic infarctiondiffusion tensor imagingin vivo cDTIradial diffusivityswine infarction model

Identifiers

PMID36032414

DOI10.3390/app12073512

PMCPMC9408809

OpenAlexW4221132580

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.