Evidence map›Paper›PMID 36032343›Full record

ArticleBritish journal of pain2022

Opioid use after outpatient elective general surgery: quantifying the burden of persistent use.

Collin Clarke, Andrew McClure, Laura Allen, Luke Hartford, Julie Ann Van Koughnett, Daryl Gray, Patrick B Murphy, Chris Vinden, Ken Leslie, Kelly N Vogt

Open access · greenAbstract read
In one paragraph

Article in British journal of pain, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Collin ClarkeLondon Health Sciences Centre, Victoria Hospital, London, ON, Canada.ORCID https://orcid.org/0000-0003-3677-5900
Andrew McClureInstitute for Clinical Evaluative Sciences (ICES) Western, London, ON, Canada.
Laura AllenLondon Health Sciences Centre, Victoria Hospital, London, ON, Canada.
Luke HartfordLondon Health Sciences Centre, Victoria Hospital, London, ON, Canada.
Julie Ann Van KoughnettLondon Health Sciences Centre, Victoria Hospital, London, ON, Canada.
Daryl GrayLondon Health Sciences Centre, Victoria Hospital, London, ON, Canada.
Patrick B MurphyDivision of Acute Care Surgery, Medical College of Wisconsin, WI, USA.
Chris VindenLondon Health Sciences Centre, Victoria Hospital, London, ON, Canada.
Ken LeslieLondon Health Sciences Centre, Victoria Hospital, London, ON, Canada.
Kelly N VogtLondon Health Sciences Centre, Victoria Hospital, London, ON, Canada.
Western University · CALondon Health Sciences Centre · CAInstitute for Clinical Evaluative Sciences · CAMedical College of Wisconsin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Surgery is a major risk factor for chronic opioid use among patients who had not recently been prescribed opioids. This study identifies the rate of, and risk factors for, persistent opioid use following laparoscopic cholecystectomy and open inguinal hernia repair in patients not recently prescribed opioids. Methods: This retrospective population-based cohort study included all patients who had not been prescribed opioids in the 6 months prior to undergoing open inguinal hernia repair or laparoscopic cholecystectomy from January 2013 to July 2016 in Ontario. Opioid prescription was identified from the provincial Narcotics Monitoring System and data were obtained from the Institute for Clinical Evaluative Sciences. The primary outcome was persistent opioid use after surgery (3, 6, 9 and 12 months). Associated risk factors and prescribing patterns were also examined. Results: Among the 90,326 patients in the study cohort, 80% filled an opioid prescription after surgery, with 11%, 9%, 5% and 1% filling a prescription at 3, 6, 9 and 12 months, respectively. Significant variability was identified in the type of opioid prescribed (41% codeine, 31% oxycodone, 18% tramadol) and in regional prescribing patterns (mean prescription/region range, 135-225 oral morphine equivalents). Predictors of continued opioid use included age, female gender, lower income quintile and being operated on by less experienced surgeons. Conclusion: Most patients who undergo elective cholecystectomy and hernia repair will fill a prescription for an opioid after surgery, and many will continue to fill opioid prescriptions for considerably longer than clinically anticipated. There is important variability in opioid type, regional prescribing patterns and risk factors that identify strategic targets to reduce the opioid burden in this patient population.

Indexed as

Abdominal painchronic painpainpain managementpostoperative pain

Identifiers

PMID36032343
PMCPMC9411755
OpenAlexW3195504784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.