Evidence map›Paper›PMID 36032128›Full record

ArticleFrontiers in immunology2022

Characterization of CD41

Li Dai, Mayuko Uehara, Xiaofei Li, Brenna A LaBarre, Naima Banouni, Takaharu Ichimura, Melissa M Lee-Sundlov, Vivek Kasinath, Jade A Sullivan, Heyu Ni and 10 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 4 countries.

Li DaiTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Mayuko UeharaTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Xiaofei LiTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Brenna A LaBarreSystems Biology and Computer Science Program, Ann Romney Center for Neurological Diseases, Department of Neurology, Brigham & Women's Hospital, Boston, MA, United States.
Naima BanouniTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Takaharu IchimuraRenal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Melissa M Lee-SundlovDivision of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Vivek KasinathTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Jade A SullivanDepartment of Laboratory Medicine and Pathobiology, and Toronto Platelet Immunobiology Group, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Heyu NiDepartment of Laboratory Medicine and Pathobiology, and Toronto Platelet Immunobiology Group, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Francesca BaroneCentre for Translational Inflammation Research, University of Birmingham, Birmingham, United Kingdom.
Silvia GianniniDivision of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Baharak BahmaniTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Peter T SageTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Nikolaos A PatsopoulosSystems Biology and Computer Science Program, Ann Romney Center for Neurological Diseases, Department of Neurology, Brigham & Women's Hospital, Boston, MA, United States.
George C TsokosDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Jonathan S BrombergDepartments of Surgery and Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, United States.
Karin HoffmeisterDivision of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Liwei JiangInstitute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.
Reza AbdiTransplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Harvard University · USBrigham and Women's Hospital · USBroad Institute · USCanadian Blood Services · CAChina Pharmaceutical University · CNChinese Academy of Sciences · CNUniversity of Birmingham · GBUniversity of Maryland, Baltimore · USUniversity of Toronto · CA

Funding

Project 3: Role of Glycosaminoglycans in HematopoiesisP01HL151333 · NHLBI · VERSITI WISCONSIN, INC. · PI HAWKRIDGE, ADAM M · 2021 to 2025
$12.3M
Reshaping lymph node stroma for transplant toleranceP01AI153003 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jonathan S Bromberg · 2020 to 2026
$9.3M
Lymph Node Structure and Function in Tolerance: Role of LamininsR01AI114496 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BROMBERG, JONATHAN S · 2015 to 2024
$4.2M
The novel role of beta3 integrin in regulating alloimmunityR01AI170193 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Jamil R Azzi · 2022 to 2026
$3.8M
Organ Design and Engineering Training Program (ODET Program)T32EB016652 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI BONVENTRE, JOSEPH VINCENT · 2014 to 2023
$3.5M
IRI, innate immunity and transplant rejectionR01AI156084 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2021 to 2025
$2.3M
NHLBI NIH HHS P01 HL151333NIAID NIH HHS P01 AI153003NIAID NIH HHS R01 AI114496NIAID NIH HHS R01 AI156084NIAID NIH HHS R01 AI170193NIBIB NIH HHS T32 EB016652
6 · The paper itself

Abstract

Lymph nodes (LNs) are the critical sites of immunity, and the stromal cells of LNs are crucial to their function. Our understanding of the stromal compartment of the LN has deepened recently with the characterization of nontraditional stromal cells. CD41 (integrin αIIb) is known to be expressed by platelets and hematolymphoid cells. We identified two distinct populations of CD41

Indexed as

Lymph NodesStromal CellsAnimalsFibroblastsHumansMiceCD41 + progenitor cellslymphaticlymphatic remodelinglymph nodesstromal cells

Identifiers

PMID36032128
PMCPMC9405417
OpenAlexW4290804022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.