ArticleBiological psychiatry global open science2022
A Social Gradient of Cortical Thickness in Adolescence: Relationships With Neighborhood Socioeconomic Disadvantage, Family Socioeconomic Status, and Depressive Symptoms.
Article in Biological psychiatry global open science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Sleep and participation in extracurricular activities moderate associations between low SES and brain structure and functional connectivity.Developmental cognitive neuroscience · 2026Article
- Individual differences in adolescent cortical development are associated with neighborhood characteristics: Longitudinal findings from the ABCD study.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Maternal mood entropy and children's hippocampal development: Enduring versus transient effects.Development and psychopathology · 2026Article
- Geographic Measures of Early Life-Course Social Exposome in the Evaluation of Structural Neuroanatomy: A Scoping Review.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Review
- Psychobiological mechanisms underlying the association between early life stress and depression in adolescence.Molecular psychiatry · 2026Review
- Neurostructural Substrates of Hierarchical Dimensions of Internalizing Symptoms in Youth.Human brain mapping · 2026Article
- Mediational Role of Executive Functions on Parental Style and Anxiety and Depression Symptoms in Adolescents From Different Vulnerability Environments: A Cross-Sectional Study.Depression and anxiety · 2026Article
- Investigating hierarchical critical periods in human neurodevelopment.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- The interplay of reward responsiveness and socioeconomic disadvantage in the prospective prediction of depression symptoms in youth.Psychological medicine · 2025Article
- Socioeconomic status, prefrontal cortical volume, and cardiometabolic risk in early adolescence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Article
- Nutritional Strategies in Major Depression Disorder: From Ketogenic Diet to Modulation of the Microbiota-Gut-Brain Axis.Molecular neurobiology · 2025Review
- The growing interdisciplinarity of developmental psychopathology: Implications for science and training.Development and psychopathology · 2024Article
- Childhood Community Disadvantage and MRI-Derived Structural Brain Integrity After Age 65 Years.JAMA network open · 2024Article
- Neurodevelopmental imprints of sociomarkers in adolescent brain connectomes.Scientific reports · 2024Article
- Neighborhood disadvantage and parenting predict longitudinal clustering of uncinate fasciculus microstructural integrity and clinical symptomatology in adolescents.Developmental cognitive neuroscience · 2024Article
- Neighborhood Socioeconomic Disadvantage and White Matter Microstructure of the Arcuate Fasciculus and Uncinate Fasciculus in Adolescents.Biological psychiatry global open science · 2024Article
- Article
- Characterizing the dimensional structure of early-life adversity in the Adolescent Brain Cognitive Development (ABCD) Study.Developmental cognitive neuroscience · 2023Article
- Reduced cortical surface area globally and in reward-related cortex is associated with elevated depressive symptoms in preschoolers.Journal of affective disorders · 2022Article
- Introduction to the Special Issue on the Exposome-Understanding Environmental Impacts on Brain Development and Risk for Psychopathology.Biological psychiatry global open science · 2022Article
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5 authors.
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Abstract
backgroundMental and physical health are affected by family and neighborhood socioeconomic status (SES). Accelerated maturation in the context of lower SES is one mechanism that might contribute to underlying health disparities; few studies, however, have considered neighborhood SES in relation to putative markers of brain maturation in adolescents.
methodsIn 120 adolescents 13 to 18 years of age, we examined family and neighborhood SES in relation to cortical thickness adjusted for age. We also examined whether cortical thickness was related to depressive symptoms and explored regions of interest.
resultsControlling for age, neighborhood socioeconomic disadvantage was associated with a thinner cortex in the left hemisphere (standardized β = -0.20), which was related to more severe depressive symptoms (standardized β = -0.33). Family SES was not significantly associated with age-adjusted mean cortical thickness in either hemisphere after controlling for relevant covariates. In exploratory, covariate-adjusted analyses of cortical thickness at the regional level, neighborhood socioeconomic disadvantage was associated with reduced cortical thickness in the left superior frontal gyrus (standardized β = -0.27), fusiform gyrus (standardized β = -0.20), and insula (standardized β = -0.21), whereas family SES was positively associated with cortical thickness in the right lateral and right medial orbitofrontal cortex (standardized β = 0.21 and standardized β = 0.19, respectively) and left transverse temporal gyrus (standardized β = 0.22).
conclusionsOur findings provide evidence for a social gradient of cortical thickness during adolescence. Adolescents living in less advantaged community or family contexts appear to have a thinner cortex according to global and regional measures. Reduced cortical thickness in the left hemisphere may indicate increased risk for depression in adolescence.
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