Evidence map›Paper›PMID 36031936›Full record

ArticleAnnals of geriatric medicine and research2022

Calf Circumference Measurement Protocols for Sarcopenia Screening: Differences in Agreement, Convergent Validity and Diagnostic Performance.

Melissa Rose Berlin Piodena-Aportadera, Sabrina Lau, Justin Chew, Jun Pei Lim, Noor Hafizah Ismail, Yew Yoong Ding, Wee Shiong Lim

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Annals of geriatric medicine and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06903832 (Discharge Recommendations for Older Adults Using Physical Outcome Measure), which is not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06903832 recruitingnot on this mapstarted 2025, after this paper: background citation

Discharge Recommendations for Older Adults Using Physical Outcome Measure (DROP)

TypeobservationalSponsorNational University Hospital, SingaporeRan2025 to 2026Enrolled60ConditionsDischarge Planning, Older Adults (65 Years and Older), Acute Hospitalization, OUTCOME MEASURES
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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  9. Indirect estimates of cellular hydration and relative water content and their associations with muscle strength and physical function in older adults: a path analysis from the Pro-Eva study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Melissa Rose Berlin Piodena-AportaderaDepartment of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
Sabrina LauDepartment of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
Justin ChewDepartment of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
Jun Pei LimDepartment of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
Noor Hafizah IsmailInstitute of Geriatrics and Active Aging, Tan Tock Seng Hospital, Singapore.
Yew Yoong DingDepartment of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
Wee Shiong LimDepartment of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
Tan Tock Seng Hospital · SG

Funding

Lee Foundation
6 · The paper itself

Abstract

backgroundAlthough recommended by the Asian Working Group for Sarcopenia 2019 consensus (AWGS'19) as a screening tool for sarcopenia, there remains no consensus regarding the position (sitting, standing) or laterality (right, left) for the measurement of calf circumference (CC). This study aimed to determine the agreement between CC measurements, correlations with muscle mass and function, and diagnostic performance for sarcopenia screening.

methodsWe studied 176 healthy community-dwelling older adults (mean age, 66.8±7.1 years) from the GERILABS-2 study. CC was measured using non-elastic tape in four ways: left and right sides in the sitting and standing positions. Sarcopenia was diagnosed using the AWGS'19 criteria. We produced Bland-Altman plots to assess the agreement, partial correlations for muscle mass and function to compare convergent validity, and area under the receiver operating characteristic curve (AUC) to compare diagnostic performance.

resultsThe prevalence rate of sarcopenia was 17.4%. Sitting CC was larger than standing regardless of laterality (right 35.31±2.95 cm vs. 34.61±2.74 cm; left 35.37±2.96 cm vs. 34.70±2.83 cm; both p<0.001), consistent with the systematic bias on Bland-Altman plots showing the overestimation of sitting over standing measurements (right bias=0.70 cm; 95% confidence interval [CI], -0.48-1.88; left bias=0.67 cm, 95% CI, -0.35-1.68). After adjusting for age and sex, CC was significantly correlated with appendicular skeletal mass, hand grip strength, knee extension, gait speed, chair stand, and short physical performance battery. Although right-sided CC measurements had better diagnostic performance (AUC=0.817), the difference was not statistically significant compared to the other positions (p>0.05). The optimal cutoff was <34 cm for all measurements, except for the left standing position (cutoff <35 cm).

conclusionStanding CC measurements are recommended for sarcopenia screening in community-dwelling older adults because of their good agreement without systematic bias, convergent validity, and diagnostic performance.

Indexed as

ProtocolSarcopeniaScreening

Identifiers

PMID36031936
PMCPMC9535367
OpenAlexW4293426222

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.