Evidence map›Paper›PMID 36031888›Full record

ArticleClinical hemorheology and microcirculation2022

Red blood cell sedimentation rate measurements in a high aspect ratio microchannel.

Andreas Passos, Marinos Louka, Charalambos Vryonidis, Antonis Inglezakis, Constantinos Loizou, Elena Nikiphorou, Savvas Psarelis, Efstathios Kaliviotis

Open access · bronzeAbstract read
In one paragraph

Article in Clinical hemorheology and microcirculation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Andreas PassosDepartment of Mechanical Engineering and Material Science and Engineering, Cyprus University of Technology, Limassol, Cyprus.
Marinos LoukaDepartment of Mechanical Engineering and Material Science and Engineering, Cyprus University of Technology, Limassol, Cyprus.
Charalambos VryonidisDepartment of Mechanical Engineering and Material Science and Engineering, Cyprus University of Technology, Limassol, Cyprus.
Antonis InglezakisEMBIO Diagnostics Ltd, Nicosia, Cyprus.
Constantinos LoizouEMBIO Diagnostics Ltd, Nicosia, Cyprus.
Elena NikiphorouCentre for Rheumatic Diseases, King's College London, London, UK.
Savvas PsarelisMinistry of Health Cyprus, Nicosia, Cyprus.
Efstathios KaliviotisDepartment of Mechanical Engineering and Material Science and Engineering, Cyprus University of Technology, Limassol, Cyprus.
Cyprus University of Technology · CYKing's College London · GBMinistry of Health · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe erythrocyte sedimentation rate (ESR) test is commonly used in clinical practice for monitoring, screening and diagnosing pathological conditions and diseases related to the inflammatory response of the immune system. Several ESR techniques have been developed over the years improving the reliability, the precision and the duration of the measurement.

objectiveIn the present study a new low cost micro-ESR technique is described providing the major advantage of reducing the measurement time and the blood sample volume by multiple times compared to the commercial methods.

methodsBlood samples were obtained from healthy donors within the age group of 24-28 years and the haematocrit was adjusted to 30%, 40% and 50%. The ESR of the samples was measured utilizing a surface tension driven (STD) microfluidic chip and a monitoring device.

resultsThe evaluation of the method showed a high correlation (0.94, p < 10-5) at all haematocrit levels with the commercial instrument indicating the feasibility of the technique.

conclusionsThis micro-ESR technique provides the potential for a simple, low cost and fast tool for ESR measurement using low blood volume acquired by finger prick.

Indexed as

Hematologic DiseasesMicrovesselsAdultBlood SedimentationErythrocytesHematocritHumansReproducibility of ResultsYoung AdultErythrocyte sedimentation rate (ESR)micro-ESRmicrofluidicspoint-of-caresurface tension driven flow

Identifiers

PMID36031888
PMCPMC9881021
OpenAlexW4292749547

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.