Evidence map›Paper›PMID 36031785›Full record

ArticleYonsei medical journal2022

Axial Length as a Risk Factor for Steroid-Induced Ocular Hypertension.

Wungrak Choi, Jung Dong Kim, Hyoung Won Bae, Chan Yun Kim, Gong Je Seong, Min Kim

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Frequency-dependent risk of steroid-induced ocular hypertension.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  10. Baseline intraocular pressure: an independent risk factor in severe steroid-induced ocular hypertension after intravitreal dexamethasone implant.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wungrak ChoiInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3015-2502
Jung Dong KimInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4023-9211
Hyoung Won BaeInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8421-5636
Chan Yun KimInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8373-9999
Gong Je SeongInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. gjseong@yuhs.ac.ORCID https://orcid.org/0000-0002-5456-4296
Min KimInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. minkim76@gmail.com.ORCID https://orcid.org/0000-0003-1873-6959
Yonsei University · KR

Funding

National Research Foundation of Korea NRF-2019R1A2C1091089National Research Foundation of Korea NRF-2022R1I1A1A01071919Yonsei University College of Medicine 6-2020-0139
6 · The paper itself

Abstract

purposeIn this study, we aimed to assess whether axial length (AXL) is a true risk factor for steroid-induced ocular hypertension (OHT). We hypothesized that the proportion of patients with steroid-induced OHT among individuals who have received intravitreal dexamethasone (DEX) injections would differ according to the AXL of their eyes. MATERIALS AND

methodsA single-center, cross-sectional, case-control study was conducted on 467 eyes that underwent DEX implant injection owing to various retinal diseases. Intraocular pressure (IOP) was measured before the injection and 1 week and 1, 2, 3, 6, and 12 months after the injection. Enrolled patients were divided into OHT and normal IOP groups. Univariable logistic regression analysis was used to calculate odds ratios of steroid-induced OHT with significant variables being analyzed using a multivariable model.

resultsA longer AXL was identified as a risk factor for steroid-induced OHT via both univariable and multivariable analyses, with an odds ratio of 1.216 [95% confidence interval (CI): 1.004-1.472,

conclusionOur findings indicate that a long AXL is a risk factor for steroid-induced OHT. Further, clinicians should be aware of steroid-induced OHT when treating patients with high myopia with steroids.

Indexed as

GlaucomaOcular HypertensionCase-Control StudiesCross-Sectional StudiesDexamethasoneGlucocorticoidsHumansIntraocular PressureIntravitreal InjectionsRisk FactorsDexamethasoneGlucocorticoidsaxial lengthDexamethasoneintraocular pressuremyopiaocular hypertension

Identifiers

PMID36031785
PMCPMC9424783
OpenAlexW4293111706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.