Evidence map›Paper›PMID 36031706›Full record

ArticleNMR in biomedicine2023

Self-gated, dynamic contrast-enhanced magnetic resonance imaging with compressed-sensing reconstruction for evaluating endothelial permeability in the aortic root of atherosclerotic mice.

Claudia Calcagno, John A David, Abdallah G Motaal, Bram F Coolen, Thijs Beldman, Alexandra Corbin, Arnav Kak, Sarayu Ramachandran, Alison Pruzan, Arthi Sridhar and 5 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Claudia CalcagnoBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, USA.ORCID 0000-0002-4325-8728
John A DavidAmsterdam University Medical Centers, Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Abdallah G MotaalSiemens Healthineers, Cardiovascular Care Group, Advanced Therapies Business, Erlangen, Germany.
Bram F CoolenAmsterdam University Medical Centers, Department of Biomedical Engineering and Physics, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Thijs BeldmanDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Alexandra CorbinBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Arnav KakUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Sarayu RamachandranBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Alison PruzanBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Arthi SridharDepartment of Hematology/Oncology, UTHealth McGovern Medical School, Houston, TX, USA.
Raphael SolerCNRS, CRMBM, Marseille, France.
Christopher M FariesBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Zahi A FayadBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Willem J M MulderBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Gustav J StrijkersBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Icahn School of Medicine at Mount Sinai · USAmsterdam University Medical Centers · NLRadboud University Nijmegen · NLCentre National de la Recherche Scientifique · FRSiemens Healthineers (Germany) · DEThe University of Texas Health Science Center · USThe University of Texas Southwestern Medical Center · US

Funding

Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Zahi A. Fayad · 2017 to 2026
$24.3M
MR/PET Imaging of coronary atherosclerosisR01HL071021 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI FAYAD, ZAHI A. · 2002 to 2019
$7.8M
Theranostic HDL nanoparticles for inflammatory macrophages in atherosclerosisR01EB009638 · NIBIB · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2009 to 2016
$4.6M
Ga68-DOTATATE PET imaging of plaque inflammationR01HL135878 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2017 to 2020
$2.9M
Cardiovascular Inflammation Reduction Trial (CIRT) - Inflammation Imaging StudyR01HL128056 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2015 to 2018
$2.6M
PET/MRI to study nanotherapy in atherosclerosisR01HL125703 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM · 2015 to 2018
$2.4M
NHLBI NIH HHS P01 HL131478NHLBI NIH HHS R01 HL071021NHLBI NIH HHS R01 HL125703NHLBI NIH HHS R01 HL128056NHLBI NIH HHS R01 HL135878NIBIB NIH HHS R01 EB009638
6 · The paper itself

Abstract

High-risk atherosclerotic plaques are characterized by active inflammation and abundant leaky microvessels. We present a self-gated, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) acquisition with compressed sensing reconstruction and apply it to assess longitudinal changes in endothelial permeability in the aortic root of Apoe

Indexed as

Aorta, ThoracicContrast MediaAnimalsDisease ProgressionFemaleMagnetic Resonance ImagingMiceContrast MediaatherosclerosisDCE-MRIinflammationmicrovascularizationmouseself-gated

Identifiers

PMID36031706
PMCPMC10078106
OpenAlexW4293514574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.