Evidence map›Paper›PMID 36031642›Full record

ArticleNeurological research and practice2022

Management of medication overuse (MO) and medication overuse headache (MOH) S1 guideline.

Hans-Christoph Diener, Peter Kropp, Thomas Dresler, Stefan Evers, Stefanie Förderreuther, Charly Gaul, Dagny Holle-Lee, Arne May, Uwe Niederberger, Sabrina Moll and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurological research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 6 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 6 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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  16. Hallmarks of primary headache: part 1 - migraine.The journal of headache and pain · 2024
    Review
  17. Article
  18. Article
  19. Medication-overuse headache: a narrative review.The journal of headache and pain · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Hans-Christoph DienerAbteilung Für Neuroepidemiologie, Institut Für Medizinische Informatik, Biometrie Und Epidemiologie (IMIBE), Universität Duisburg-Essen, Hufelandstraße 55, 45147, Essen, Germany. hans.diener@uk-essen.de.ORCID http://orcid.org/0000-0002-6556-8612
Peter KroppInstitut Für Medizinische Psychologie Und Medizinische Soziologie, Universitätsmedizin Rostock, Zentrum Für Nervenheilkunde, Gehlsheimer Straße 20, 18147, Rostock, Germany.
Thomas DreslerKlinik Für Psychiatrie Und Psychotherapie, Graduiertenschule & Forschungsnetzwerk LEAD, Universität Tübingen, Calwerstraße 14, 72074, Tübingen, Germany.
Stefan EversChefarzt der Neurologischen Klinik II, Krankenhaus Lindenbrunn, Postfach 1120, 31861, Coppenbrügge, Germany.
Stefanie FörderreutherNeurologische Klinik, Ludwig-Maximilians-Universität München, Neurologischer Konsildienst Der LMU, Innenstadtklinikum, Ziemssenstraße 1, 80336, Munich, Germany.
Charly GaulKopfschmerzzentrum Frankfurt, Dalbergstr. 2a, 65929, Frankfurt, Germany.
Dagny Holle-LeeKlinik Für Neurologie Und Westdeutsches Kopfschmerzzentrum, Universitätsklinikum Essen, Hufelandstraße 55, 45128, Essen, Germany.
Arne MayInstitut Für Systemische Neurowissenschaften, Universitätsklinikum Hamburg, Eppendorf (UKE), Gebäude W34, 3. Stock, Martinistraße 52, 20246, Hamburg, Germany.
Uwe NiederbergerInstitut Für Medizinische Psychologie Und Medizinische Soziologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Preußerstraße 1- 9, 24105, Kiel, Germany.
Sabrina MollPsychologische Praxis, Rothschildallee 16, 60389, Frankfurt am Main, Germany.
Christoph SchankinOberarzt, Universitätsklinik Für Neurologie, Inselspital Bern, Freiburgstrasse 4, 3010, Bern, Germany.
Christian LamplOrdensklinikum Linz, Krankenhaus der Barmherzigen Schwestern Linz Betriebsgesellschaft M.B.H., Seilerstätte 4, 4010, Linz, Germany.
Essen University Hospital · DEInstitut für Medizinische Informatik, Biometrie und Epidemiologie · DEKrankenhaus Lindenbrunn · DELudwig-Maximilians-Universität München · DEUniversität Hamburg · DEUniversitätsmedizin Rostock · DEUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic headache due to the overuse of medication for the treatment of migraine attacks has a prevalence of 0.5-2.0%. This guideline provides guidance for the management of medication overuse (MO) and medication overuse headache (MOH). RECOMMENDATIONS: Treatment of headache due to overuse of analgesics or specific migraine medications involves several stages. Patients with medication overuse (MO) or medication overuse headache (MOH) should be educated about the relationship between frequent use of symptomatic headache medication and the transition from episodic to chronic migraine (chronification), with the aim of reducing and limiting the use of acute medication. In a second step, migraine prophylaxis should be initiated in patients with migraine and overuse of analgesics or specific migraine drugs. Topiramate, onabotulinumtoxinA and the monoclonal antibodies against CGRP or the CGRP-receptor are effective in patients with chronic migraine and medication overuse. In patients with tension-type headache, prophylaxis is performed with amitriptyline. Drug prophylaxis should be supplemented by non-drug interventions. For patients in whom education and prophylactic medication are not effective, pausing acute medication is recommended. This treatment can be performed in an outpatient, day hospital or inpatient setting. Patients with headache due to overuse of opioids should undergo inpatient withdrawal. The success rate of the stepped treatment approach is 50-70% after 6 to 12 months. A high relapse rate is observed in patients with opioid overuse. Tricyclic antidepressants, neuroleptics (antiemetics) and the administration of steroids are recommended for the treatment of withdrawal symptoms or headaches during the medication pause. Consistent patient education and further close monitoring reduce the risk of relapse.

Indexed as

ManagementMedication overuseMedication overuse headacheMigraineMigraine attack

Identifiers

PMID36031642
PMCPMC9422154
OpenAlexW4293510963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.