Evidence map›Paper›PMID 36031621›Full record

ArticleBMC medical ethics2022

From a voluntary vaccination policy to mandatory vaccination against COVID-19 in cancer patients: an empirical and interdisciplinary study in bioethics.

Henri-Corto Stoeklé, Sakina Sekkate, Elisabeth Angellier, Titouan Kennel, Asmahane Benmaziane, May Mabro, Jean-François Geay, Philippe Beuzeboc, Christian Hervé

Open access · goldAbstract read
In one paragraph

Article in BMC medical ethics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Vaccination against HPV: Easier said than done?Human vaccines & immunotherapeutics · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Henri-Corto Stoeklé *Department of Ethics and Scientific Integrity, Foch Hospital, Suresnes, France.
Sakina Sekkate *Department of Oncology and Supportive Care, Foch Hospital, Suresnes, France.
Elisabeth AngellierDepartment of Supportive and Palliative Care, Institut Curie, Saint-Cloud, France.
Titouan KennelDepartment of Clinical Research and Innovation, Foch Hospital, Suresnes, France.
Asmahane BenmazianeDepartment of Oncology and Supportive Care, Foch Hospital, Suresnes, France.
May MabroDepartment of Oncology and Supportive Care, Foch Hospital, Suresnes, France.
Jean-François GeayDepartment of Oncology and Supportive Care, Foch Hospital, Suresnes, France.
Philippe Beuzeboc *Department of Oncology and Supportive Care, Foch Hospital, Suresnes, France.
Christian Hervé *Department of Ethics and Scientific Integrity, Foch Hospital, Suresnes, France. c.herve@hopital-foch.com.
Hôpital Foch · FRInstitut Curie · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAt the start of 2021, oncologists lacked the necessary scientific knowledge to adapt their clinical practices optimally when faced with cancer patients refusing or reluctant to be vaccinated against COVID-19, despite the marked vulnerability of these patients to severe, and even fatal forms of this new viral infectious disease. Oncologists at Foch Hospital were confronted with this phenomenon, which was observed worldwide, in both the general population and the population of cancer patients.

methodsBetween April and November 2021, the Ethics and Oncology Departments of Foch Hospital decided to investigate this subject, through an empirical and interdisciplinary study in bioethics. Our scientific objective was to try to identify and resolve the principal bio-ethical issues, with a view to improving clinical practices in oncology during future major pandemics of this kind, from a highly specific bio-ethical standpoint (= quality of life/survival). We used a mainly qualitative methodological approach based on questionnaires and interviews.

resultsIn April 2021, 29 cancer patients refused or were reluctant to be vaccinated (5.6%; 29/522). Seventeen of these patients said that making vaccination mandatory would have helped them to accept vaccination. In October 2021, only 10 cancer patients continued to maintain their refusal (1.9%; 10/522). One of the main reasons for the decrease in refusals was probably the introduction of the "pass sanitaire" (health pass) in July 2021, which rendered vaccination indispensable for many activities. However, even this was not sufficient to convince these 10 cancer patients.

conclusionWe identified a key bio-ethical issue, which we then tried to resolve: vaccination policy. We characterized a major tension between "the recommendation of anti-COVID-19 vaccination" (a new clinical practice) and "free will" (a moral value), and the duty to "protect each other" (a moral standard). Mandatory vaccination, at least in France, could resolve this tension, with positive effects on quality of life (i.e. happiness), or survival, in cancer patients initially refusing or reluctant to be vaccinated, but only if collective and individual scales are clearly distinguished.

Indexed as

BioethicsCOVID-19NeoplasmsHumansInterdisciplinary StudiesPolicyQuality of LifeVaccinationBioethicsCancerCOVID-19FranceHospitalOncologyPandemicVaccine

Identifiers

PMID36031621
PMCPMC9420182
OpenAlexW4293677255

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.