Evidence map›Paper›PMID 36030740›Full record

ArticleCell calcium2022

KRAP is required for diffuse and punctate IP

Irene Vorontsova, Jeffrey T Lock, Ian Parker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell calcium, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Pacemaking in the lymphatic system.The Journal of physiology · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Inter-membrane control of junctional InsPTrends in cell biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. An integrate-and-fire approach to CaBiophysical journal · 2023
    Article
  10. IPContact (Thousand Oaks (Ventura County, Calif.))
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Irene VorontsovaDepartment of Neurobiology & Behavior, UC Irvine, Irvine, CA, United States.
Jeffrey T LockDepartment of Neurobiology & Behavior, UC Irvine, Irvine, CA, United States.
Ian ParkerDepartment of Neurobiology & Behavior, UC Irvine, Irvine, CA, United States; Department of Physiology & Biophysics, UC Irvine, Irvine, CA, United States. Electronic address: iparker@uci.edu.

Funding

Elementary Events of Intracellular Calcium SignalingR37GM048071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PARKER, IAN · 2011 to 2020
$5.3M
SPATIAL AND TEMPORAL ASPECTS OF INSP3 SIGNALLINGR01GM048071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PARKER, IAN · 1992 to 2010
$3.9M
NIGMS NIH HHS R01 GM048071NIGMS NIH HHS R37 GM048071
6 · The paper itself

Abstract

KRas-induced actin-interacting protein (KRAP) has been identified as crucial for the appropriate localization and functioning of the inositol trisphosphate receptors (IP

Indexed as

CalciumCalcium SignalingHEK293 CellsHumansInositol 1,4,5-Trisphosphate ReceptorsMembrane ProteinsMicrofilament ProteinsProto-Oncogene Proteins p21(ras)RNA, Small InterferingCalciumInositol 1,4,5-Trisphosphate ReceptorsITPRID2 protein, humanMembrane ProteinsMicrofilament ProteinsProto-Oncogene Proteins p21(ras)RNA, Small InterferingCalcium fluctuation imagingCalcium puffsCalcium wavesIP(3) receptorKRAP

Identifiers

PMID36030740
PMCPMC9588678

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.