SynthesisDevelopmental cognitive neuroscience2022
The brain in social context: A systematic review of substance use and social processing from adolescence to young adulthood.
Synthesis in Developmental cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- How childhood adversity affects components of decision making.Neuroscience and biobehavioral reviews · 2025Pooled it
- Validation of the English Social Attunement Questionnaire: Associations with Substance Use, Impulsivity, and Sensation Seeking across the Lifespan.European addiction research · 2026Article
- The role of peer influence in shaping developmental trajectories of substance use expectancies in early adolescence.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Risk calculation circuit abnormalities plus psychosocial risk variables predict problematic substance use in youth with externalizing disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Social closeness and reward sensitivity enhance corticostriatal function during experiences of shared rewards.Biological psychology · 2026Article
- Predicting individual differences in digital alcohol intervention effectiveness through multimodal data.NPJ digital medicine · 2026Article
- Article
- Impact of problematic substance use and social anxiety on school functioning: Insights from the Texas Youth Depression and Suicide Research Network.PLOS mental health · 2026Article
- Social Closeness and Reward Sensitivity Enhance Corticostriatal Function during Experiences of Shared Rewards.bioRxiv : the preprint server for biology · 2025Article
- Neural responses to peers moderate conversation-drinking associations in daily life.Scientific reports · 2025Article
- Implicit Social Attunement and Alcohol Use: The Effect of Peer Feedback on Willingness to Drink in Social Settings.International journal of mental health and addiction · 2025Article
- A comparative study of state self-esteem responses to social media feedback loops in adolescents and adults.Frontiers in psychology · 2025Article
- Corticostriatal responses to social reward are linked to trait reward sensitivity and subclinical substance use in young adults.Social cognitive and affective neuroscience · 2024Article
- Expanding understanding of adolescent neural sensitivity to peers: Using social information processing theory to generate new lines of research.Developmental cognitive neuroscience · 2024Review
- Corticostriatal Responses to Social Reward are Linked to Trait Reward Sensitivity and Subclinical Substance Use in Young Adults.bioRxiv : the preprint server for biology · 2024Article
- Probable depression and its correlates among undergraduate students in Johannesburg, South Africa.Frontiers in psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Substance use escalates between adolescence and young adulthood, and most experimentation occurs among peers. To understand underlying mechanisms, research has focused on neural response during relevant psychological processes. Functional magnetic resonance imaging (fMRI) research provides a wealth of information about brain activity when processing monetary rewards; however, most studies have used tasks devoid of social stimuli. Given that adolescent neurodevelopment is sculpted by the push-and-pull of peers and emotions, identifying neural substrates is important for intervention. We systematically reviewed 28 fMRI studies examining substance use and neural responses to stimuli including social reward, emotional faces, social influence, and social stressors. We found substance use was positively associated with social-reward activity (e.g., in the ventral striatum), and negatively with social-stress activity (e.g., in the amygdala). For emotion, findings were mixed with more use linked to heightened response (e.g., in amygdala), but also with decreased response (e.g., in insula). For social influence, evidence supported both positive (e.g., cannabis and nucleus accumbens during conformity) and negative (e.g., polydrug and ventromedial PFC during peers' choices) relations between activity and use. Based on the literature, we offer recommendations for future research on the neural processing of social information to better identify risks for substance use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.