ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2022
Burden of caregiving for cardiovascular dysautonomia in Parkinson's disease.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 7 citations in OpenAlex.
- Caregiver Burden and Psychological Distress Among Informal Caregivers for Individuals with Dementia in the Republic of Kazakhstan: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- Nonmotor fluctuations in Parkinson's disease: impact on caregiving and quality of life.Journal of neurology · 2025Observational
- Association between autonomic dysfunction with motor and non-motor symptoms in patients with Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- Baseline prevalence and longitudinal assessment of autonomic dysfunction in early Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- Epidemiology of autonomic dysfunction in Parkinson's disease (Review).Medicine internationalReview
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Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe sought to estimate the impact of cardiovascular autonomic neuropathy (cAN) on informal caregivers of patients with Parkinson's disease (PD), defined as individuals providing regular care to a friend, partner, or family member with PD, and to evaluate the mutual relationship between caregiver burden and patient health-related quality of life (HRQoL).
methodsWe enrolled 36 consecutive patients with PD and their informal caregivers. Patients underwent a detailed motor, autonomic, cognitive, and functional assessment. Caregivers were assessed using the Zarit Burden Interview (ZBI). Differences in caregiver burden, expressed by the ZBI score, and strength of association between caregiver burden, cAN, and HRQoL were assessed using analysis of covariance (ANCOVA), logistic regression, and linear regression analyses. Analyses were adjusted for patients' age, PD duration, and motor and cognitive disability, as well as caregivers' age.
resultsModerate-severe caregiver burden was reported in 41.7% of PDcAN
conclusionThese results highlight the significant impact of cAN on PD caregivers and the need for targeted interventions addressing this frequently overlooked and insufficiently treated source of nonmotor disability in PD.
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