Evidence map›Paper›PMID 36030372›Full record

ArticleThe Veterinary record2023

Moxidectin use in Scottish sheep flocks suggests a need for clearer product labelling and communication of updated SCOPS guidelines.

Jennifer McIntyre, Laura Miskell, Eric R Morgan, Fiona Lovatt, Roz Laing

Open access · hybridAbstract read
In one paragraph

Article in The Veterinary record, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jennifer McIntyreSchool of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK.ORCID 0000-0003-2579-6693
Laura MiskellInstitute for Global Food Security, Queen's University Belfast, Belfast, UK.
Eric R MorganInstitute for Global Food Security, Queen's University Belfast, Belfast, UK.ORCID 0000-0002-5999-7728
Fiona LovattFlock Health, Barnard Castle, UK.ORCID 0000-0003-2298-9174
Roz LaingSchool of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK.ORCID 0000-0002-6191-0759
Queen's University Belfast · GBUniversity of Glasgow · GBFlock (United Kingdom) · GB

Funding

Wellcome Trust 216614/Z/19/Z
6 · The paper itself

Abstract

backgroundGuidelines for sustainable use of moxidectin were established in 2020. This study aimed to identify how Scottish sheep farmers are using this key endectocide and estimate its effectiveness against gastrointestinal nematodes.

methodsQuestionnaires were distributed to sheep farmers across Scotland, and analysis focused on moxidectin use in relation to Sustainable Control of Parasites in Sheep (SCOPS) guidelines. Farmers using moxidectin in their flock volunteered to submit post-treatment sheep faecal samples, which were analysed for the presence of gastrointestinal nematodes using faecal egg counts with polymerase chain reaction to determine species.

resultsDespite 70% of farmers using moxidectin in 2020, knowledge levels varied: 24% of farmers included other anthelmintics when asked about moxidectin use. Moxidectin was used for a wide variety of reasons, and most farmers did not consistently follow SCOPS guidelines. Despite only 2 of 76 farmers reporting failure of moxidectin treatment, gastrointestinal nematodes were found following moxidectin treatment on five out of six farms tested and included Teladorsagia circumcincta, Cooperia curticei, Haemonchus contortus and Nematodirus sp.

conclusionFindings from this project indicate the need for improved anthelmintic product labelling and farmer support to encourage sustainable use. The presence of nematodes in treated animals is suggestive of anthelmintic resistance.

Indexed as

AnthelminticsNematodaSheep DiseasesAnimalsCommunicationDrug ResistanceFecesMacrolidesParasite Egg CountProduct LabelingScotlandSheepAnthelminticsMacrolidesmoxidectin

Identifiers

PMID36030372
PMCPMC10087414
OpenAlexW4293570295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.