ArticleBMC gastroenterology2022
Systemic immune-inflammation index within the first postoperative hour as a predictor of severe postoperative complications in upper abdominal surgery: a retrospective single-center study.
Article in BMC gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Intrathecal Morphine in Addition to Serratus Anterior Plane Block and Dexmedetomidine on Postoperative Recovery (QoR-15) and Systemic Inflammation in Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
Evaluation of the Effects of Different Intraoperative Warming Techniques on Core Body Temperature and Hematologic Inflammatory Indices (SII, NLR, PLR, LMR) in Patients Undergoing Laparoscopic Cholecystectomy: A Prospective Randomized Controlled Study
Who cites it
12 citing papers in PubMed.
- Article
- Comparison of T-tilt, Trendelenburg, and dorsal lithotomy positions in retrograde intrarenal surgery: surgical, inflammatory, and efficiency outcomes.International urology and nephrology · 2026Article
- Association between systemic immune-inflammation index and mortality in patients admitted to the intensive care unit after urgent or elective major abdominal surgery.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Observational
- Systemic Inflammatory Indices Predict Survival and Limb Outcomes after Revascularization for Chronic Limb-Threatening Ischemia.Journal of vascular research · 2026Article
- Inflammatory Markers may Determine Postoperative Complications in Cases of Peritoneal Carcinomatosis of Ovarian Origin Treated With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.Journal of surgical oncology · 2026Article
- Perioperative predictors of delayed recovery after pancreatic and biliary surgeries: The role of hematologic indices.SAGE open medicine · 2026Article
- Preoperative Aggregate Index of Systemic Inflammation is Associated with 30-Day Postoperative Pneumonia After Minimally Invasive Esophagectomy for Esophageal Squamous Cell Carcinoma: A Retrospective Cohort Study.Infection and drug resistance · 2026Article
- Prognostic Impact of Postoperative Systemic Immune-Inflammation Index Changes in Epithelial Ovarian Cancer.Cancers · 2025Article
- Nomogram model for predicting pressure injury in COPD patients using SII: a Chinese clinical study.Frontiers in medicine · 2025Article
- Article
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundSystemic pro-inflammatory factors play a critical role in mediating severe postoperative complications (SPCs) in upper abdominal surgery (UAS). The systemic immune-inflammation index (SII) has been identified as a new inflammatory marker in many occasions. The present study aims to determine the association between SII and the occurrence of SPCs after UAS.
methodsIncluded in this study were 310 patients with upper abdominal tumors who received UAS and subsequently were transferred to the anesthesia intensive care unit between November 2020 and November 2021 in Nanjing Drum Hospital. SPCs, including postoperative pulmonary complications (PPCs), major adverse cardiac and cardiovascular events, postoperative infections and delirium, were recorded during the hospital stay. The clinical features of the patients with and without SPCs were compared by Student's t-test or Fisher's exact test as appropriate. Risk factors associated with SPC occurrence were evaluated by univariable and multivariable logistic regression analyses. Receiver operating characteristic (ROC) curve analysis was used to establish a cut-off level of SII value to predict SPCs.
resultsOf the 310 patients receiving UAS, 103 patients (33.2%) presented at least one SPC, including PPCs (n = 62), adverse cardiovascular events (n = 22), postoperative infections (n = 51), and delirium (n = 5). Both preoperative SII and 1-h postoperative SII in patients with SPCs were significantly higher than those in patients without SPCs. Multivariate analysis showed that 1-h postoperative SII was an independent predictor for SPC occurrence (OR = 1.000, 95% CI 1.000-1.000, P = 0.007), together with postoperative C-reactive protein, postoperative arterial lactate, postoperative oxygenation-index and older age. The ROC curve showed that the optimal cutoff value of 1-h postoperative SII to predict SPCs was 754.6078 × 10
conclusionOur findings demonstrated an association between the higher level of 1-h postoperative SII and SPCs, suggesting that 1-h postoperative SII, especially categorized 1-h postoperative SII using cutoff value, may be a useful tool for identifying patients at risk of developing SPCs.
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Registered trials
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