Evidence map›Paper›PMID 36029524›Full record

ArticleInternational journal of epidemiology2023

Impact of the COVID-19 pandemic on total, sex- and age-specific all-cause mortality in 20 countries worldwide during 2020: results from the C-MOR project.

Christiana A Demetriou, Souzana Achilleos, Annalisa Quattrocchi, John Gabel, Elena Critselis, Constantina Constantinou, Nicoletta Nicolaou, Giuseppe Ambrosio, Catherine M Bennett, Nolwenn Le Meur and 27 more

Erratum issuedAbstract read
In one paragraph

Article in International journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

37 authors.

Christiana A DemetriouDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Souzana AchilleosDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Annalisa QuattrocchiDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
John GabelUniversity of Nicosia Medical School, Nicosia, Cyprus.
Elena CritselisDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Constantina ConstantinouDepartment of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.
Nicoletta NicolaouDepartment of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.
Giuseppe AmbrosioDepartment of Medicine, University of Perugia School of Medicine, Perugia, Italy.
Catherine M BennettInstitute for Health Transformation, Deakin University, Burwood, Australia.
Nolwenn Le MeurUniversity of Rennes, EHESP, CNRS, Inserm, Arènes-UMR 6051, RSMS-U 1309, Rennes, France.ORCID 0000-0001-8451-4014
Julia A CritchleyPopulation Health Research Institute, St George's, University of London, London, UK.
Laust Hvas MortensenDepartment of Methods and Analysis, Statistics Denmark, Copenhagen Oe, Denmark.
Jose Manuel Rodriguez-LlanesEuropean Commission Joint Research Centre, Ispra, VA, Italy.ORCID 0000-0003-3736-736X
Mario ChongDepartamento de Ingeniería, Universidad del Pacífico, Lima, Peru.
Gleb DenissovEstonian Causes of Death Registry, National institute for Health Development, Tallinn, Estonia.
Petra KlepacDepartment of Communicable Diseases, National Institute of Public Health, Ljubljana, Slovenia.
Lucy P GoldsmithInstitute for Infection and Immunity, and Population Health Research Institute, St George's, University of London, London, UK.
Antonio José Leal CostaInstitute of Studies in Collective Health (IESC), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Terje P HagenDepartment of Health Management and Health Economics, Institute of Health and Society, University of Oslo, Oslo, Norway.
Marie Chan SunDepartment of Medicine, Faculty of Medicine and Health Sciences, University of Mauritius, Réduit, Mauritius.
Qian HuangDepartment of Geography, Center for Rural and Primary Healthcare, University of South Carolina, Columbia, SC, USA.
Nataliia PidmurniakDepartment of Medicine, Bogomolets National Medical University, Kyiv, Ukraine.
Inbar ZuckerSchool of Public Health, Ministry of Health, Ramat Gan, Israel.
Joseph CuthbertsonDisaster Resilience Initiative, Monash University, Clayton,VIC, Australia.
Bo BurströmDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Manuel BarronDepartment of Economics, Universidad del Pacifico Av Sanchez Cerro, Lima, Peru.
Ivan ErženSchool of Public Health, National Institute of Public Health, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.
Fabrizio StracciPublic Health Section, Department of Medicine and Surgery, University of Perugia, Piazza Lucio Severi, Perugia, Italy.
Wilson CalmonInstitute of Mathematics and Statistics, Fluminense Federal University, Niteroi, Brazil.
Cyndy MartialDepartment of Demography, Statistics Mauritius, LIC Centre, Port Louis, Mauritius.
Olesia VerstiukUniversity of Nicosia Medical School, Nicosia, Cyprus.
Zalman KaufmanIsraeli Center of Disease Control, Ministry of Health, Ramat Gan, Israel.
Wenjing TaoDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Maia KereselidzeNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Nino ChikhladzeFaculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.
Antonis PolemitisUniversity of Nicosia, Nicosia, Cyprus.
Andreas CharalambousUniversity of Nicosia Medical School, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo understand the impact of the COVID-19 pandemic on mortality, this study investigates overall, sex- and age-specific excess all-cause mortality in 20 countries, during 2020.

methodsTotal, sex- and age-specific weekly all-cause mortality for 2015-2020 was collected from national vital statistics databases. Excess mortality for 2020 was calculated by comparing weekly 2020 observed mortality against expected mortality, estimated from historical data (2015-2019) accounting for seasonality, long- and short-term trends. Crude and age-standardized rates were analysed for total and sex-specific mortality.

resultsAustria, Brazil, Cyprus, England and Wales, France, Georgia, Israel, Italy, Northern Ireland, Peru, Scotland, Slovenia, Sweden, and the USA displayed substantial excess age-standardized mortality of varying duration during 2020, while Australia, Denmark, Estonia, Mauritius, Norway, and Ukraine did not. In sex-specific analyses, excess mortality was higher in males than females, except for Slovenia (higher in females) and Cyprus (similar in both sexes). Lastly, for most countries substantial excess mortality was only detectable (Austria, Cyprus, Israel, and Slovenia) or was higher (Brazil, England and Wales, France, Georgia, Italy, Northern Ireland, Sweden, Peru and the USA) in the oldest age group investigated. Peru demonstrated substantial excess mortality even in the <45 age group.

conclusionsThis study highlights that excess all-cause mortality during 2020 is context dependent, with specific countries, sex- and age-groups being most affected. As the pandemic continues, tracking excess mortality is important to accurately estimate the true toll of COVID-19, while at the same time investigating the effects of changing contexts, different variants, testing, quarantine, and vaccination strategies.

Indexed as

COVID-19Age FactorsFemaleFranceHumansItalyMaleMortalityPandemicsall-cause mortalityCOVID-19excess mortalityglobal impactinfection controlpandemicSARS-CoV-2

Identifiers

PMID36029524
PMCPMC9452146

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.