ArticleEuropean heart journal. Quality of care & clinical outcomes2022
Critical Care Cardiology Trials Network (CCCTN): a cohort profile.
Article in European heart journal. Quality of care & clinical outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06265714 (The IndONEsia ICCU Registry), which is not on this map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia
Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Variation in Vasoactive Treatment Selection for Cardiogenic Shock: Insights From the Critical Care Cardiology Trials Network (CCCTN).Circulation. Heart failure · 2026Article
- Generalizability of Landmark Temporary MCS Device Trials: Insights From the CSWG Registry.JACC. Advances · 2026Article
- Cardiogenic Shock and the Role of Critical Care Cardiology: Evidence, Models of Care, and Future Directions.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Review
- Cardiogenic shock: from standardization to precision-a new era in critical care cardiology?Intensive care medicine · 2026Article
- Evolution of Critical Care Cardiology: An Update on Structure, Care Delivery, Training, and Research Paradigms: A Scientific Statement From the American Heart Association.Journal of the American College of Cardiology · 2025Article
- Anemia as a potent marker of in-hospital mortality in patients admitted to the cardiac intensive care unit: Data from the Critical Care Cardiology Trials Network (CCCTN) Registry.Journal of intensive medicine · 2025Article
- Left Ventricular Mechanical Circulatory Support Devices for Cardiogenic Shock After Myocardial Infarction.Cardiology and therapy · 2025Review
- Review
- Hepatic Biomarker Abnormalities in the Cardiac Intensive Care Unit: Proposed Criteria for Cardiohepatic Syndrome.JACC. Advances · 2025Article
- Characteristics and Outcomes of Adults With Congenital Heart Disease in the Cardiac Intensive Care Unit.JACC. Advances · 2024Article
- Contemporary Risk Models for In-Hospital and 30-Day Mortality After Percutaneous Coronary Intervention.Current cardiology reports · 2024Review
- Sex-specific and ethnicity-specific differences in MINOCA.Nature reviews. Cardiology · 2024Review
- Family Engagement in the Adult Cardiac Intensive Care Unit: A Survey of Family Engagement Practices in the Cardiac Critical Care Trials Network.Circulation. Cardiovascular quality and outcomes · 2023Article
- Trials and Tribulations of Inotrope Choice in Cardiogenic Shock With Renal Dysfunction.JACC. Advances · 2023Article
- Presentation and Outcomes of Patients With Preoperative Critical Illness Undergoing Cardiac Surgery.JACC. Advances · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
47 authors at 20 institutions in 2 countries.
Funding
Abstract
aimsThe aims of the Critical Care Cardiology Trials Network (CCCTN) are to develop a registry to investigate the epidemiology of cardiac critical illness and to establish a multicentre research network to conduct randomised clinical trials (RCTs) in patients with cardiac critical illness. METHODS AND
resultsThe CCCTN was founded in 2017 with 16 centres and has grown to a research network of over 40 academic and clinical centres in the United States and Canada. Each centre enters data for consecutive cardiac intensive care unit (CICU) admissions for at least 2 months of each calendar year. More than 20 000 unique CICU admissions are now included in the CCCTN Registry. To date, scientific observations from the CCCTN Registry include description of variations in care, the epidemiology and outcomes of all CICU patients, as well as subsets of patients with specific disease states, such as shock, heart failure, renal dysfunction, and respiratory failure. The CCCTN has also characterised utilization patterns, including use of mechanical circulatory support in response to changes in the heart transplantation allocation system, and the use and impact of multidisciplinary shock teams. Over years of multicentre collaboration, the CCCTN has established a robust research network to facilitate multicentre registry-based randomised trials in patients with cardiac critical illness.
conclusionThe CCCTN is a large, prospective registry dedicated to describing processes-of-care and expanding clinical knowledge in cardiac critical illness. The CCCTN will serve as an investigational platform from which to conduct randomised controlled trials in this important patient population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.