Evidence map›Paper›PMID 36029194›Full record

ArticleJournal of cellular and molecular medicine2022

Increase in membrane surface expression and phosphorylation of TRPC3 related to olfactory dysfunction in α-synuclein transgenic mice.

Min Chen, Jia Liu, Hanjiang Luo, Chunli Duan, Ge Gao, Hui Yang

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Min ChenDepartment of Neurobiology School of Basic Medical Sciences, Key Laboratory of Neural Regeneration and Repair, Center for Parkinson's Disease, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China.ORCID 0000-0002-2308-9031
Jia LiuDepartment of Neurobiology School of Basic Medical Sciences, Key Laboratory of Neural Regeneration and Repair, Center for Parkinson's Disease, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Hanjiang LuoGuangxi Neurological Disease Clinical Research Center, Laboratory of Neuroscience, Affiliated Hospital of Guilin Medical University, Guilin, China.
Chunli DuanDepartment of Neurobiology School of Basic Medical Sciences, Key Laboratory of Neural Regeneration and Repair, Center for Parkinson's Disease, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Ge GaoDepartment of Neurobiology School of Basic Medical Sciences, Key Laboratory of Neural Regeneration and Repair, Center for Parkinson's Disease, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Hui YangDepartment of Neurobiology School of Basic Medical Sciences, Key Laboratory of Neural Regeneration and Repair, Center for Parkinson's Disease, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Capital Medical University · CNGuilin Medical University · CN

Funding

Beijing Municipal Commission of Health and Family Planning PXM2019-026283-000002National Natural Science Foundation of China 81760241National Natural Science Foundation of China 81870994Scientific Research and Technology Development Program of Guangxi 2019GXNSFDA245015Scientific Research and Technology Development Program of Guangxi AD18281014
6 · The paper itself

Abstract

Olfactory impairment is an initial non-motor symptom of Parkinson's disease that causes the deposition of aggregated α-synuclein (α-syn) in olfactory neurons. Transient receptor potential canonical (TRPC) channels are a diverse group of non-selective Ca

Indexed as

alpha-SynucleinOlfaction DisordersTRPC Cation ChannelsAnimalsCalciumMiceMice, TransgenicPhosphorylationalpha-SynucleinCalciumTRPC3 cation channelTRPC Cation Channelsdysosmiaolfactory neuronsParkinson's diseaseTRPC3α-Synuclein

Identifiers

PMID36029194
PMCPMC9549507
OpenAlexW4293367346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.