Evidence map›Paper›PMID 36029186›Full record

ArticlePhysiological reports2022

Impact of sex and sex hormones on pathophysiology and progression of aortic stenosis in a murine model.

Marie-Ange Fleury, Mohamed-Salah Annabi, Martine Voisine, Maxime Hervault, Anne-Julie Boilard, Mylène Shen, André Marette, Nancy Côté, Marie-Annick Clavel

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Sex-related hormonal variances and clinical outcomes in TAVR patients.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  3. Article
  4. Effect of Estrogen on Sirt1 Signaling in Human Macrophages.International journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Marie-Ange FleuryInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.
Mohamed-Salah AnnabiInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.
Martine VoisineInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.
Maxime HervaultInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.
Anne-Julie BoilardInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.
Mylène ShenInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.
André MaretteInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.
Nancy CôtéInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.
Marie-Annick ClavelInstitut universitaire de cardiologie et de pneumologie de Québec-Université Laval / Québec Heart and Lung Institute, Université Laval, Québec city, Canada.ORCID 0000-0002-8924-740X
Institut universitaire de cardiologie et de pneumologie de Québec · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lesions observed in AS have been shown to be sex specific, with women presenting extensive fibrotic remodeling while men developing more calcification deposit. We thus aimed to evaluate the influence of sex and sex hormones on the pathophysiology of aortic valve stenosis (AS) in our mouse model of AS. LDLr

Indexed as

Aortic Valve StenosisCalcinosisAnimalsAortic ValveDisease Models, AnimalFemaleGonadal Steroid HormonesHumansMaleMiceTestosteroneGonadal Steroid HormonesTestosteroneaortic stenosispathophysiologysex differences

Identifiers

PMID36029186
PMCPMC9419154
OpenAlexW4293365899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.