Evidence map›Paper›PMID 36029063›Full record

ArticleInternational journal of fertility & sterility2022

Comparison of Side Effects of COVID-19 Vaccines: Sinopharm, AstraZeneca, Sputnik V, and Covaxin in Women in Terms of Menstruation Disturbances, Hirsutism, and Metrorrhagia: A Descriptive-Analytical Cross-Sectional Study.

Amirsaleh Abdollahi, Iman Naseh, Fatemeh Kalroozi, Mohammad Hassan Kazemi-Galougahi, Maryam Nezamzadeh, Shayan Sabeti Billandi, Mojtaba Yousefi Zoshk

Open access · greenAbstract read
In one paragraph

Article in International journal of fertility & sterility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Menstrual Cycle Disturbances after COVID-19 Vaccination: A Cross-Sectional Study.International journal of fertility & sterility · 2024
    Article
  6. Abnormal uterine bleeding diagnoses and care following COVID-19 vaccination.American journal of obstetrics and gynecology · 2024
    Article
  7. Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amirsaleh AbdollahiMazandaran University of Medical Sciences, Sari, Iran.ORCID 0000-0001-5715-7322
Iman NasehDepartment of Infectious Diseases, Faculty of Medicin, Aja University of Medical Sciences, Tehran, Iran. Email: imna3030@gmail.com.ORCID 0000-0002-4016-7660
Fatemeh KalrooziDepartment of Pediatric Nursing, Faculty of Nursing, Aja University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-2966-6108
Mohammad Hassan Kazemi-GalougahiDepartment of Social Medicine, Faculty of Medicine, Aja University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-4601-6457
Maryam NezamzadehDepartment of critical Nursing, Faculty of Nursing, Aja University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-4466-5819
Shayan Sabeti BillandiMazandaran University of Medical Sciences, Sari, Iran.ORCID 0000-0001-9373-6065
Mojtaba Yousefi ZoshkDepartment of Trauma, Faculty of Medicin, Aja University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-3329-4776
Aja University of Medical Sciences · IRMazandaran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPresent study assessed whether Sinopharm, AstraZeneca, Sputnik V, and Covaxin's vaccinated women<br />reveal a distinct incidence of menstruation disturbances, hirsutism, and metrorrhagia.<br />Materials and Methods: Data collection was performed from June to August 2021, and 427 women working in seven<br />selected hospitals in Tehran were studied in this descriptive-analytical cross-sectional study. All of these women had<br />received one or both doses of the vaccines with one of the assessed vaccines. Required data was collected via questionnaire<br />and imported to SPSS 16 for further assessment and analysis. Fisher's Exact Test and Chi-Squared test were<br />main statistical tests used to understand whether any significant relation exists or not.<br />Results: The participant's mean age and body mass index (BMI) were 29.78 ± 10.55 and 23.27 ± 3.82, respectively.<br />Three hundred ninety-five cases (92.4%) had received both doses of the vaccines. Also, 154 cases (36.1%) had a history<br />of COVID-19. A total of 38 cases (8.8%) of menstruation disturbances, 20 cases (4.6%) of metrorrhagia, and 7<br />cases (1.6%) of hirsutism were reported after receiving the vaccines. There was a significant difference among the<br />vaccinated groups with the vaccines as mentioned earlier in terms of menstruation disturbances (hypermenorrhea,<br />dysmenorrhea, Amenorrhea) (P=0.01). The highest and the lowest incidence of menstruation disturbances were recorded<br />in the group vaccinated with Covaxin (17.6%) and Sputnik V (5%), respectively. There was also no significant<br />difference amongst the vaccinated groups with the four vaccines regarding the incidence of metrorrhagia and<br />hirsutism (P=0.10 and P=0.12, respectively). There was no significant relationship between all three complications<br />incidence with the previous infection concerning all vaccines (coefficient=0.46, 1.27, -0.15 respectively for menstruation<br />disturbances, metrorrhagia, and, hirsutism).<br />Conclusion: Seemingly, Covaxin revealed the most side effects in terms of menstruation disturbances. As a result, professionals<br />must carry out several studies with reasonable samples to recommend the vaccine to those women confidently.

Indexed as

COVID-19 VaccinesHirsutismMenstrual CycleMetrorrhagiaSide effects

Identifiers

PMID36029063
PMCPMC9396006
OpenAlexW4293677538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.