ArticleInternational journal of fertility & sterility2022
Early Postpartum Glucose Intolerance, Metabolic Syndrome and Gestational Diabetes Mellitus Determinants after Assisted Conception: A Prospective Cohort Study.
Article in International journal of fertility & sterility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Pooled it
- Antenatal glycemic control in gestational diabetes and its association with postpartum glucose intolerance and weight retention.Clinics (Sao Paulo, Brazil) · 2026Article
- Association of sleep variability and irregularity with gestational metabolic syndrome: a birth cohort study.Frontiers in endocrinology · 2026Article
- Dose-response association between OGTT and adverse perinatal outcomes after IVF treatment: A cohort study based on a twin population.Journal of endocrinological investigation · 2025Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to determine the prevalence of postpartum metabolic syndrome (MetS), glucose intolerance,<br />and the determinants, 6-12 weeks postpartum in women with assisted reproduction technology conception<br />gestational diabetes mellitus diagnosis (ART-GDM) compared to women with spontaneous conception and GDM<br />diagnosis (SC-GDM).<br />Materials and Methods: In this prospective cohort study, two groups consisting of 62 ART-GDM and 64 SC-GDM<br />singleton pregnant women were followed 6-12 weeks after delivery for postpartum MetS. Fasting glucose, 75-g 2-h<br />OGTT, and lipid profile were assessed. Waist and hip circumference, and systolic and diastolic blood pressures (BP)<br />were measured at postpartum. Clinical, paraclinical, and obstetric data were recorded from registry offices. The prevalence<br />of MetS and glucose intolerance were determined. Predictors of MetS and glucose intolerance were evaluated<br />by logistic regression.<br />Results: The prevalence of postpartum MetS was 20.8% in ART-GDM women and 10.9% in SC-GDM (P=0.123).<br />Mean postpartum BMI and systolic BP were significantly higher in the ART-GDM group (P=0.016 and P=0.027<br />respectively). Adverse pregnancy outcomes were significantly higher in the ART-GDM group. Postpartum glucose<br />intolerance prevalence did not vary significantly between the groups. Family history of diabetes was a predictive factor<br />for postpartum MetS and glucose intolerance 6-12 weeks after delivery.<br />Conclusion: Early postpartum MetS and glucose intolerance prevalence after assisted conception did not vary significantly;<br />however, postpartum body mass index (BMI) and systolic BP were significantly higher in the ART-GDM group.<br />Lifestyle modification programs and long-term health care of ART women with GDM diagnosis can be recommended.<br />Further studies with larger sample size and longer follow-up are necessary to verify our findings.
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