ArticleThe New phytologist2022
Comparative transcriptomics and metabolomics reveal specialized metabolite drought stress responses in switchgrass (Panicum virgatum).
Article in The New phytologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 66 citations in OpenAlex.
- Discovery of the rosalexin pathway expands the modular network of maize diterpenoid phytoalexins.Research square · 2026Article
- Article
- Novel Cell-Type-Specific Drought-Responsive Proteins in Root Tips of Field-Grown Perennial Switchgrass.ACS omega · 2026Article
- Genome-wide discovery and characterization of terpene synthases contributing to strawberry aroma metabolism.Plant physiology · 2026Article
- Integrated transcriptomic and metabolomic analyses reveal drought-response mechanisms in Suriana maritima from tropical coral islands.BMC plant biology · 2026Article
- Developmentally specific physiological and metabolic responses support drought resilience in switchgrass and constrain biofuel yield.Journal of experimental botany · 2026Article
- Response of sorghum (Sorghum bicolor (L.) Moench) to various-duration of drought: physiology, transcriptome, and weighted gene co-expression network analysis.BMC plant biology · 2026Article
- Rhizomicrobiomes from Drought-Adapted Mediterranean Species Differently Alter Leaf Metabolome ofPlants (Basel, Switzerland) · 2026Article
- Integrated physiological, transcriptomic and metabolomic analysis reveals differential cold response in wheat seedlings across varieties.Frontiers in plant science · 2026Article
- The role of isoprenoids in the chemical interaction between plants and other organisms in their rhizosphere.aBIOTECH · 2025Review
- Leaf Anatomical and Transcriptomic Coordination Underlies Drought Resilience in Psammophytes.International journal of molecular sciences · 2025Article
- Unearthing the hidden organ: vital role of the root in drought tolerance of plants.Plant molecular biology · 2025Review
- A model for the adaptation of Euryale ferox leaves to aquatic environments through EfCGT1-controlled flavonoid C-glycoside-specific accumulation in epidermis cells.Plant biotechnology journal · 2025Article
- Characterization of switchgrass (Panicum virgatum L.) PvKSL1 as a levopimaradiene/abietadiene-type diterpene synthase.Plant biology (Stuttgart, Germany) · 2025Article
- Integrated transcriptome and metabolome analysis revealed differential drought stress response mechanisms of wheat seedlings with varying drought tolerance.BMC plant biology · 2025Article
- Comparative transcriptome and metabolome profiling unveil genotype-specific strategies for drought tolerance in cotton.Frontiers in plant science · 2025Article
- Integrating Physiology, Transcriptome, and Metabolome Analyses Reveals the Drought Response in Two Quinoa Cultivars with Contrasting Drought Tolerance.International journal of molecular sciences · 2024Article
- CYP76BK1 orthologs catalyze furan and lactone ring formation in clerodane diterpenoids across the mint family.The Plant journal : for cell and molecular biology · 2024Article
- CYP76BK1 orthologs catalyze furan and lactone ring formation in clerodane diterpenoids across the mint family.bioRxiv : the preprint server for biology · 2024Article
- Disentangling plant- and environment-mediated drivers of active rhizosphere bacterial community dynamics during short-term drought.Nature communications · 2024Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
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Abstract
Switchgrass (Panicum virgatum) is a bioenergy model crop valued for its energy efficiency and drought tolerance. The related monocot species rice (Oryza sativa) and maize (Zea mays) deploy species-specific, specialized metabolites as core stress defenses. By contrast, specialized chemical defenses in switchgrass are largely unknown. To investigate specialized metabolic drought responses in switchgrass, we integrated tissue-specific transcriptome and metabolite analyses of the genotypes Alamo and Cave-in-Rock that feature different drought tolerance. The more drought-susceptible Cave-in-Rock featured an earlier onset of transcriptomic changes and significantly more differentially expressed genes in response to drought compared to Alamo. Specialized pathways showed moderate differential expression compared to pronounced transcriptomic alterations in carbohydrate and amino acid metabolism. However, diterpenoid-biosynthetic genes showed drought-inducible expression in Alamo roots, contrasting largely unaltered triterpenoid and phenylpropanoid pathways. Metabolomic analyses identified common and genotype-specific flavonoids and terpenoids. Consistent with transcriptomic alterations, several root diterpenoids showed significant drought-induced accumulation, whereas triterpenoid abundance remained predominantly unchanged. Structural analysis verified select drought-responsive diterpenoids as oxygenated furanoditerpenoids. Drought-dependent transcriptome and metabolite profiles provide the foundation to understand the molecular mechanisms underlying switchgrass drought responses. Accumulation of specialized root diterpenoids and corresponding pathway transcripts supports a role in drought stress tolerance.
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