Evidence map›Paper›PMID 36028789›Full record

SynthesisCerebellum (London, England)2023

Effects of Cerebellar Transcranial Direct Current Stimulation in Patients with Stroke: a Systematic Review.

Li Hong-Yu, Zhang Zhi-Jie, Li Juan, Xiong Ting, He Wei-Chun, Zhu Ning

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Cerebellum (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. The Cerebellar Connectome Disruptions in Ischemic Stroke.CNS neuroscience & therapeutics · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Li Hong-YuGeneral Hospital of Ningxia Medical University, Yinchuan, 750003, China. 792292024@qq.com.
Zhang Zhi-JieYinchuan Stomatology Hospital, Yinchuan, 750002, China.
Li JuanGeneral Hospital of Ningxia Medical University, Yinchuan, 750003, China.
Xiong TingGeneral Hospital of Ningxia Medical University, Yinchuan, 750003, China.
He Wei-ChunGeneral Hospital of Ningxia Medical University, Yinchuan, 750003, China.
Zhu NingGeneral Hospital of Ningxia Medical University, Yinchuan, 750003, China.
Ningxia Medical University General Hospital · CNNingxia Medical University · CNYinchuan First People's Hospital · CN

Funding

Scientific Research Project of Ningxia Health Commission 2019-NW-009
6 · The paper itself

Abstract

backgroundThe cerebellum is involved in regulating motor, affective, and cognitive processes. It is a promising target for transcranial direct current stimulation (tDCS) intervention in stroke.

objectivesTo review the current evidence for cerebellar tDCS (ctDCS) in stroke, its problems, and its future directions.

methodsWe searched the Web of Science, MEDLINE, CINAHL, EMBASE, Cochrane Library, and PubMed databases. Eligible studies were identified after a systematic literature review of the effects of ctDCS in stroke patients. The changes in assessment scale scores and objective indicators after stimulation were reviewed.

resultsEleven studies were included in the systematic review, comprising 169 stroke patients. Current evidence suggests that anode tDCS on the right cerebellar hemisphere does not appear to enhance language processing in stroke patients. Compared with the sham group, stroke patients showed a significant improvement in the verb generation task after cathodal ctDCS stimulation. However, with regard to naming, two studies came to the opposite conclusion. The contralesional anodal ctDCS is expected to improve standing balance but not motor learning in stroke patients. The bipolar bilateral ctDCS protocol to target dentate nuclei (PO10h and PO9h) had a positive effect on standing balance, goal-directed weight shifting, and postural control in stroke patients.

conclusionsctDCS appears to improve poststroke language and motor dysfunction (particularly gait). However, the evidence for these results was insufficient, and the quality of the relevant studies was low. ctDCS stimulation parameters and individual factors of participants may affect the therapeutic effect of ctDCS. Researchers need to take a more regulated approach in the future to conduct studies with large sample sizes. Overall, ctDCS remains a promising stroke intervention technique that could be used in the future.

Indexed as

StrokeTranscranial Direct Current StimulationCerebellumHumansLanguagePostural Balance

Identifiers

PMID36028789
OpenAlexW4293467587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.