Evidence map›Paper›PMID 36028725›Full record

ArticleJournal of cancer research and clinical oncology2023

Technique to match mesorectal lymph nodes imaging findings to histopathology: node-by-node comparison.

Zixuan Zhuang, Xueqin Ma, Yang Zhang, Xuyang Yang, Mingtian Wei, Xiangbing Deng, Ziqiang Wang

Open access · greenAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zixuan ZhuangDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan Province, China.
Xueqin MaDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yang ZhangDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan Province, China.
Xuyang YangDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan Province, China.
Mingtian WeiDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan Province, China.
Xiangbing DengDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan Province, China.
Ziqiang WangDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan Province, China. wangziqiang@scu.edu.cn.
Sichuan University · CNChongqing Medical University · CN

Funding

1·3·5 project for disciplines of excellence, West China Hospital, Sichuan University 2019HXFH031; 20HXJS003Department of Science and Technology of Sichuan Province 2021YFS0025Ethicon Excellent in Surgery Grant (EESG) HZB-20190528-4Post-Doctor Research Project, West China Hospital, Sichuan University 2021HXBH033
6 · The paper itself

Abstract

backgroundLymph node status is critical for staging rectal cancer and determining neoadjuvant therapy regimens. Establishing a matching between imaging and histopathological lymph nodes is fundamental for predicting lymph node status. This study reports a technique to achieve node-by-node pairing of mesorectal lymph nodes between imaging findings and histopathology.

methodsFifty-two patients with histopathologically verified rectal cancer underwent magnetic resonance imaging before surgery. The status of each lymph node in the surgical specimens was analyzed histopathologically and matched with preoperative imaging after the operation.

resultsA total of 346 mesorectal lymph nodes were located on imaging evaluation, of which 313 were confirmed histopathologically, and 33 were unmatched. The total success rate of the technique was 90.5%. Node-by-node analysis revealed 280 benign and 33 malignant nodal structures.

conclusionThe technique to match mesorectal lymph node imaging findings to histopathology was feasible and effective. It simplified the technical method and had a reasonable success matching rate, which could provide a standardized approach for obtaining a prospective correlation between imaging and histological findings, supporting all subsequent related studies at the level of mesorectal lymph nodes.

Indexed as

Lymph NodesRectal NeoplasmsHumansLymphatic MetastasisMagnetic Resonance ImagingNeoplasm StagingProspective StudiesRectumHistopathologyMesorectal lymph nodesMRINode-by-nodeRectal cancer

Identifiers

PMID36028725
PMCPMC11798157
OpenAlexW4293428130

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.