Evidence map›Paper›PMID 36028612›Full record

ReviewInflammopharmacology2022

Dysregulation of immunity in COVID-19 and SLE.

Seyyed Sina Hejazian, Seyyedeh Mina Hejazian, Farahnoosh Farnood, Sima Abedi Azar

Abstract readReview
In one paragraph

Review in Inflammopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seyyed Sina HejazianKidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Seyyedeh Mina HejazianKidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Farahnoosh FarnoodKidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. farnood_farahnoosh@yahoo.com.ORCID http://orcid.org/0000-0002-1199-6881
Sima Abedi AzarKidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Sima_abedi@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune response plays a crucial role in preventing diseases, such as infections. There are two types of immune responses, specific and innate immunity, each of which consists of two components: cellular immunity and humoral immunity. Dysfunction in any immune system component increases the risk of developing certain diseases. Systemic lupus erythematosus (SLE), an autoimmune disease in the human body, develops an immune response against its own components. In these patients, due to underlying immune system disorders and receipt of immunosuppressive drugs, the susceptibility to infections is higher than in the general population and is the single largest cause of mortality in this group. COVID-19 infection, which first appeared in late 2019, has caused several concerns in patients with SLE. However, there is no strong proof of additional risk of developing COVID-19 in patients with SLE, and in some cases, studies have shown less severity of the disease in these individuals. This review paper discusses the immune disorders in SLE and COVID-19.

Indexed as

COVID-19Lupus Erythematosus, SystemicHumansImmunity, CellularImmunity, InnateImmunosuppressive AgentsImmunosuppressive AgentsAutoimmunityCOVID-19Immune responseSystemic lupus erythematosus (SLE)

Identifiers

PMID36028612
PMCPMC9417079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.